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临床试验/NCT02831322
NCT02831322已完成不适用

A Study of Structure and Function of Radial Artery After Transradial Coronary Intervention

The First Hospital of Qinhuangdao1 个研究点 分布在 1 个国家目标入组 600 人开始时间: 2016年7月10日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
600
试验地点
1
主要终点
radial artery occlusion

研究概览

简要总结

Several approaches have been proposed to reduce the risk of RAO, including anticoagulation, immediate postprocedural sheath removal, and a small sheath/radial artery ratio. Doppler ultrasound examination showed that interrupted blood flow in RA tend to occur in the proximal end rather than distal part of the artery,which was ignored by a majority of interventional cardiologists. Different insights into occlusion location may lead to different options of sheath materials, models, catheters and puncture access. Thus, the investigators designed this present study to explore the reason of radial artery endothelial dysfuction and damage and occlusion location by flow-mediated dilation (FMD) to determine the suitable method to reduce occlusion risk during TRI.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single (Investigator)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • admitted for transradial catheterization.

排除标准

  • femoral access, arterial circulatory disease, pathological Allen tests, decompensated heart failure, chronic renal failure

结局指标

主要结局

radial artery occlusion

时间窗: 6 month

radial artery occlusion was the absence of a flow signal by Doppler ultrasound examination

次要结局

未报告次要终点

研究者

发起方
The First Hospital of Qinhuangdao
申办方类型
Other Gov
责任方
Sponsor

研究点 (1)

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