Comparison of effect of one lung ventilation(OLV) Vs two lung ventilation(TLV) in video-assisted thoracoscopic (VATS) esophagectomy: An observational study

This study is a Prospective observational study, comparing the effects of one lung ventilation(OLV) Vs two lung ventilation(TLV) in video assisted thoracoscopic(VATS) esophagectomy.Group A: Patient with One lung Ventilation (OLV) using Single Lumen Tube (SLT) and Bronchial Blocker (BB) in Lateral Position. Group B: Patient with Two Lung Ventilation (TLV) using SLT in Prone Position. After Positioning the patient, in Group A Lateral Position and In Group B Prone Position, Arterial blood gas analysis will be done for the following parameters, partial pressure of oxygen (PaO2), partial pressure of carbon dioxide (PaCO2) and (Pao2/Fio2 ratio), the ratio of PaO2 to fraction of inspired oxygen, will be measured during pre-insufflation (T1), post insufflation (20 minutes) (T2), and in the interval of 1hr (T3), 2hr (T4), 3hr (T5) intraoperatively followed by 24hr (T6), and 48hr (T7) Postoperatively. Intraoperatively episodes of desaturation with duration and action taken for the same will also be noted. Patient will be monitored throughout the surgery as per standard protocol and patient will be shifted to ICU for further monitoring. For secondary outcomes, Postoperative inflammatory parameters like body temperature, heart rate, C-reactive protein, and Total leukocyte counts will be assessed after immediate post op and at an interval of 24hr and 48hr.