NCT01041066Unknown不适用
Nicardipine Versus Labetalol During Intubation
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- hemodynamic variables (systolic blood pressure, diastolic blood pressure and mean blood pressure, heart rate)
研究概览
简要总结
The aim of this study was to compare the efficacy of nicardipine and labetalol in attenuation of cardiovascular responses to endotracheal intubation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for general anesthesia with endotracheal intubation
排除标准
- •Patients with heart failure or coronary artery disease 2-3 degree atrio-ventricular block or severe bradycardia (< 45 beats/min) asthma, bronchial spasm or chronic obstructive pulmonary disease patients with anticipated difficult intubation (Mallampati class III, IV) severe hepatic or renal dysfunction allergy or contraindication to study medication
研究组 & 干预措施
group L
Active Comparator
0.4 mg/kg labetalol
干预措施: labetalol (Drug)
group N
Active Comparator
20 ㎍/kg nicardipine
干预措施: nicardipine (Drug)
结局指标
主要结局
hemodynamic variables (systolic blood pressure, diastolic blood pressure and mean blood pressure, heart rate)
时间窗: preinduction- 10 min after intubation
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
Unknown
2 期
Oral Nifedipine Versus IV Labetalol in Severe Pre EclampsiaSevere Pre-Eclampsia, AntepartumNCT03325348Services Institute of Medical Sciences, Pakistan194
Unknown
3 期
Comparison of Intubation With Nerve Block and With Sedation in Awake PatientsIntubation ComplicationNCT01768377Tehran University of Medical Sciences70
已完成
2 期
Comparison of Labetalol and Nitroglycerin in control of blood pressure and bleeding reduction in septorhinoplasty surgerynasal surgery.Unintentional cut, puncture, perforation or haemorrhage during surgical and medical careIRCT2014021712094N4Vice Chancellor for Research, Mashhad University of Medical Science70
招募中
4 期
Postpartum Hypertension StudyPostpartum Pregnancy-Induced HypertensionPostpartum PreeclampsiaPregnancy-Induced Hypertension in PostpartumHypertensive EmergencyNCT05139238Columbia University104
尚未招募
4 期
Intravenous Nalbuphine Versus Intravenous Dexmedetomidine for Conscious Sedation in Patients Undergoing ColonoscopyColonoscopyNCT05689242Assiut University66