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临床试验/ISRCTN19646069
ISRCTN19646069已完成不适用

Short versus conventional term glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE trial

niversity Hospital Basel, Department of Internal Medicine (Switzerland)0 个研究点目标入组 390 人开始时间: 2006年3月8日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
390

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Clinical diagnosis of exacerbated COPD, defined by the presence of at least two of the following:
  • a. Change in baseline dyspnoea
  • c. Sputum (levels I ? III according to American Thoracic Society [ATS] or European Respiratory Society [ERS] criteria)
  • 2. Age =40 years
  • 3. History of =20 pack-years of cigarette smoking

排除标准

  • 1. Inability to give informed consent
  • 2. Diagnosis of asthma
  • 3. Forced expiratory volume in one second (FEV1) or Forced Vital Capacities (FVC) (Tiffenau) >70% (bedside post-bronchodilator)
  • 4. Radiological diagnosis of pneumonia
  • 5. Coexisting disease making survival of >6 months unlikely
  • 6. Pregnancy or lactation (pregnancy test mandatory for pre-menopausal women)

研究者

发起方
niversity Hospital Basel, Department of Internal Medicine (Switzerland)

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