NCT00207077已完成1 期
A Phase I Study of Cetuximab in Combination With Erlotinib in Patients With Advanced Solid Malignancies
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Safety and efficacy of the combination of Tarceva and Erbitux
研究概览
简要总结
The purpose of this study is to find a safe and effective dose of the combination of cetuximab (Erbitux) and Tarceva (erlotinib).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Measurable disease
- •Life expectancy of at least 3 months
- •Must have at least one prior chemotherapy containing a platinum
排除标准
- •Known or documented brain metastases
- •Prior cetuximab therapy
研究组 & 干预措施
A
Experimental
干预措施: Cetuximab + Erlotinib (Drug)
结局指标
主要结局
Safety and efficacy of the combination of Tarceva and Erbitux
次要结局
- Radiographic response
研究者
研究点 (1)
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