NCT02071784已完成不适用
Etude Comparative en Imagerie Par résonnance magnétique et Par Enregistrement électroencéphalographique du Couplage Neurovasculaire Dans l'Angiopathie Cadasil
Institut National de la Santé Et de la Recherche Médicale, France1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2014年7月8日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- model-derived parameters of neurovascular coupling
研究概览
简要总结
The aim of this study is to investigate using fMRI methods, EEG and dedicated mathematical models, the potential alterations of neurovascular coupling in CADASIL.
详细描述
Comparison study of parameters derived from mathematical models of neurovascular coupling and obtained using fMRI (Bold signal, ASL and EEG).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •CADASIL group: typical NOTCH3 mutation, age less than 60 years, rankin score at 0-1, active social insurance
排除标准
- •MRI contra-indications and use of any treatment known to interfere with neurovascular coupling, pregnancy, lack of informed consent
结局指标
主要结局
model-derived parameters of neurovascular coupling
时间窗: one time point
次要结局
未报告次要终点
研究者
研究点 (1)
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