Influence of Arterial Tone Changes on Cardiac Output Measurement by Pressure Recording Analytical Method
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 31
- 试验地点
- 1
- 主要终点
- Changes of cardiac output after variation of noradrenaline dose: ECO versus PRAM
研究概览
简要总结
This study evaluates the role of arterial tone in the accuracy of cardiac output (CO) measurement by Pressure Recording Analytical Method (PRAM). Patients receiving noradrenaline who need for clinical reason to change the noradrenaline dose will be enrolled. We use echocardiography as reference method of CO measurement.
详细描述
Pressure Recording Analytical Method (PRAM) is an arterial pulse contour analysis method for CO measurement. As it is an uncalibrated method, one possible reason for its inaccuracy is rapid changes in arterial tone.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •invasive blood pressure monitoring on site
- •need to start or change the dose of noradrenaline infusion for clinical reason
排除标准
- •arrhythmia
- •severe valvular insufficiency
- •pregnancy
- •low quality arterial signal
结局指标
主要结局
Changes of cardiac output after variation of noradrenaline dose: ECO versus PRAM
时间窗: Before and 30 minutes after noradrenaline dose variation
Agreement between echocardiography and PRAM in CO measurement during arterial tone changes induced by different dose of noradrenaline
次要结局
未报告次要终点
研究者
Abele Donati, MD
Professor
Università Politecnica delle Marche