NCT01552564已完成不适用
The Microcirculation in Acute Myocardial Infarction (Micro-AMI)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Microvascular obstruction
研究概览
简要总结
This study investigates the association between the microvascular resistance at the time of primary percutaneous intervention, with microvascular obstruction on CMR and blood markers of myocardial damage.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •>18 years old
- •Cardiac symptoms of > 20 mins chest pain or equivalent.
- •ECG criteria consistent with STEMI (STEMI)
- •Proceeding with percutaneous angioplasty
- •Assent/ consent to the study
排除标准
- •Known allergy to adenosine or gadolinium
- •Chronic atrial fibrillation
- •Renal impairment with eGFR <30
- •Contraindication to angiography
- •Contraindication to CMR (implanted pacemaker/ defibrillator, ferromagnetic metal implant/ injury, claustrophobia, obesity/ too large for CMR scanner)
- •Cardiogenic shock
- •Patients with special communication needs or altered consciousness.
- •Patients who do not give assent/consent to the study
结局指标
主要结局
Microvascular obstruction
时间窗: DAy 2-4
Microvascular obstruction as a percentage of the left ventricle at 2-4 days.
次要结局
未报告次要终点
研究者
Elisa McAlindon
Clinical Research Fellow
University of Bristol
研究点 (1)
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