跳至主要内容
临床试验/NCT05269095
NCT05269095Unknown不适用

Analgesic Effect of Adductor Canal Block Combined With Infiltration of the Interspace Between Popliteal Artery and the Capsule of the Knee (IPACK) Block Versus Genicular Nerves Block in Knee Arthroscopy

Tanta University0 个研究点目标入组 105 人开始时间: 2022年3月21日最近更新:
适应症

试验速览

阶段
不适用
入组人数
105
主要终点
Postoperative 24-hour rescue analgesic consumption

研究概览

简要总结

This prospective randomized controlled study is designed to investigate the postoperative analgesic effect of adductor canal block (ACB) combined with infiltration of the interspace between the popliteal artery and the capsule of posterior knee (IPACK) block compared to genicular nerves block in patients undergoing knee arthroscopy.

详细描述

Maintaining patient safety, ensuring best patient outcomes, and optimal pain relief post-operatively are of utmost concern for anesthesia providers. Adequate pain relief attenuates stress responses and long-term chronic pain complications while contributing to improved postoperative outcomes.

Knee arthroscopy is a very common procedure and very often is performed as day-case surgery. Ambulatory arthroscopic surgery of the knee is preferred by the majority of properly selected and well-informed patients. It has been reported that a significant number of patients have moderate to severe pain 24 hours after ambulatory surgery in general and knee arthroscopy in particular and pain affects the patient's activity level and satisfaction. Adductor canal block (ACB) is a popular peripheral nerve block that has been shown to decrease the pain significantly and decrease opioid consumption with minimal effect on quadriceps function. It provides analgesia to the peri-articular and intra-articular aspects of the knee joint but doesn't relieve posterior knee pain which is moderate to severe in intensity.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
21 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Age 21-60 years
  • Both genders
  • American Society of Anaesthesiologists physical status classification I - III
  • Patients scheduled for elective unilateral knee arthroscopy under spinal anesthesia

排除标准

  • Patient refusal
  • Preoperative neurological deficits
  • Opioid-dependent (opioid intake more than 3 months)
  • Chronic pain conditions
  • Significant cardiac and respiratory disease
  • Pre-existing major organ dysfunction such as hepatic and renal failure
  • Coexisting hematological disorder or deranged coagulation parameters
  • Psychiatric illnesses
  • Allergy to any of the drugs used in the study

结局指标

主要结局

Postoperative 24-hour rescue analgesic consumption

时间窗: 24 hours postoperative

Total postoperative 24-hour rescue analgesic consumption will be recorded

次要结局

  • Post-operative pain(24 hours Postoperative)
  • Time taken till 1st rescue analgesic request(24 hours Postoperative)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Muhammad Ahmed Kandil

Resident of Anesthesiology and Surgical Intensive Care and Pain Medicine

Tanta University

相似试验