TCTR20190724005招募中未知
Comparison of efficacy and safety of pioglitazone versus metformin for moderate-to-severe chronic plaque psoriasis in patients with prediabetes or newly-diagnosed diabetes who have never taken anti-diabetic agents: a parallel, randomized, open-label,
Dermatological Society of Thailand (pending)0 个研究点目标入组 40 人开始时间: 2019年7月24日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 100 Years（—）
- 性别
- All
入选标准
- •-Minimum 18 Years
- •-Extensive chronic plaque-type psoriasis (at least 5% body surface area involvement)
- •-Prediabetes (fasting blood glucose 100-125 mg/dL or HbA1C 5.7-6.4%) or diabetes mellitus (fasting blood glucose > 126 mg/dL or HbA1C > 6.5)
排除标准
- •-Pregnancy or lactation
- •-History of pioglitazone or metformin allergy
- •-Congestive heart failure (NYHA class III or IV) or ischemic heart disease
- •-History of diabetic ketoacidosis
- •-Impaired hepatic function (>2.5 times upper range limit)
- •-Impaired renal function (estimated glomerular filtration rate < 30 mL/min per 1.73 m²)
- •-Obesity (body mass index > 30 kg/m2)
- •-Alcoholism
- •-History of bladder cancer
- •-History of bony fracture
研究者
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