Testing the Efficacy, Feasibility and Acceptability of a Pharmacist-Delivered Medication Therapy Management Approach to Smoking Cessation for Rural Smokers in Appalachia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Retention
研究概览
简要总结
Adult smokers were recruited through an independent pharmacy in rural Appalachia and were randomized to 1 of 8 treatments, including medication and/or therapy from the pharmacist, to help quit smoking.
详细描述
24 adult smokers were recruited through an independent pharmacy in rural Appalachia were randomized to 1 of 8 treatments: (1) pharmacist delivered QuitAid intervention (Yes vs. No), (2) Combination NRT Gum + NRT Patch (vs. NRT patch), and/or (3) 8 weeks of NRT (vs. standard 4 weeks). All participants received 4 weeks of NRT patch in addition to the components to which they were assigned. Participants completed baseline and 3-month follow-up assessments. The primary outcomes were feasibility of recruitment and randomization, retention, treatment adherence and fidelity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •smokers must have smoked at least 5 cigarettes per day for the past 6 months
- •be willing to set a quit date in the next 30 days
- •own a cell phone
- •be over 18 years of age
- •not be pregnant or planning to become pregnant in the next 6 months
- •not have any medical contraindications to using NRT
排除标准
- •Those who are pregnant or plan to be
- •Those under 18 years of age
- •Those with a medical contradiction
- •Those who do not own a cell phone
- •Those who have not smoked 5 cigarettes per day for the last 6 months
- •Those who are unwilling to set a quit date within 30 days
研究组 & 干预措施
QuitAid, 8 weeks, Patch + Gum
Participants received QuitAid, a medication therapy management delivered by their pharmacists and 8 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch and the NRT Gum
干预措施: Nicotine patch (Drug)
QuitAid, 8 weeks, Patch + Gum
Participants received QuitAid, a medication therapy management delivered by their pharmacists and 8 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch and the NRT Gum
干预措施: Nicotine gum (Drug)
QuitAid, 4 weeks, Patch + Gum
Participants received QuitAid, a medication therapy management delivered by their pharmacists and 4 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch and the NRT Gum
干预措施: Nicotine patch (Drug)
QuitAid, 8 weeks, Patch + Gum
Participants received QuitAid, a medication therapy management delivered by their pharmacists and 8 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch and the NRT Gum
干预措施: Medication Therapy Management (Behavioral)
QuitAid, 4 weeks, Patch + Gum
Participants received QuitAid, a medication therapy management delivered by their pharmacists and 4 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch and the NRT Gum
干预措施: Nicotine gum (Drug)
QuitAid, 4 weeks, Patch + Gum
Participants received QuitAid, a medication therapy management delivered by their pharmacists and 4 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch and the NRT Gum
干预措施: Medication Therapy Management (Behavioral)
QuitAid, 8 weeks, Patch
Participants received QuitAid, a medication therapy management delivered by their pharmacists and 8 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch
干预措施: Nicotine patch (Drug)
QuitAid, 8 weeks, Patch
Participants received QuitAid, a medication therapy management delivered by their pharmacists and 8 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch
干预措施: Medication Therapy Management (Behavioral)
QuitAid, 4 weeks, Patch
Participants received QuitAid, a medication therapy management delivered by their pharmacists and 4 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch
干预措施: Nicotine patch (Drug)
QuitAid, 4 weeks, Patch
Participants received QuitAid, a medication therapy management delivered by their pharmacists and 4 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch
干预措施: Medication Therapy Management (Behavioral)
No QuitAid, 8 weeks, Patch + Gum
Participants received 8 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch and the NRT Gum
干预措施: Nicotine patch (Drug)
No QuitAid, 8 weeks, Patch + Gum
Participants received 8 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch and the NRT Gum
干预措施: Nicotine gum (Drug)
No QuitAid, 4 weeks, Patch + Gum
Participants received 4 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch and the NRT Gum
干预措施: Nicotine patch (Drug)
No QuitAid, 4 weeks, Patch + Gum
Participants received 4 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch and the NRT Gum
干预措施: Nicotine gum (Drug)
No QuitAid, 8 weeks, Patch
Participants received 8 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch
干预措施: Nicotine patch (Drug)
No QuitAid, 4 weeks, Patch
Participants received 4 weeks of Nicotine Replacement Therapy (NRT) in the form of the NRT Patch
干预措施: Nicotine patch (Drug)
结局指标
主要结局
Retention
时间窗: 3 months
Retention was assessed by the proportion of smokers who completed the 3-month follow-up.
Feasibility of recruitment
时间窗: 3 months
Feasibility of recruitment was measured by (a) the proportion of smokers recruited from each source (e.g., ask-advise-connect, posters, prescription bag advertisements) and (b) the number recruited per month.
Feasibility of randomization
时间窗: 3 months
Feasibility of randomization was determined by the number of smokers that were approached and screened in order to randomize 24 smokers (e.g., ineligible smokers, smokers that do not consent).
次要结局
- Tobacco Use(3 months)
研究者
Melissa Little, PhD, MPH
Associate Professor, Department of Public Health Sciences
University of Virginia