The effect of yoga interventions in prevention of pregnancy complications in high risk pregnancies - A randomized controlled obstetric Doppler trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- Maternal Blood Pressure
研究概览
简要总结
Objectives: Previous studies have shown yoga to be effective in improving outcomes in normal pregnancies. This randomized controlled single-blinded trial investigated its effects on the outcomes of high-risk pregnancies. Methods: 68 high-risk pregnant women were randomized into two groups: yoga and control. The yoga group (n=30) received standard care plus one hour of meditative yoga sessions, three times a week, from the 12th to 28th week gestation. The control group (n=38) received only standard care. Fetal measurements and pregnancy complications were assessed. Results: Significantly fewer SGA babies were born in the study group (p=0.033). Both the APGAR1 and APGAR5 scores were significantly improved in the yoga group (p=0.006). Significantly fewer PIH, preeclampsia, GDM and IUGR cases were observed in the yoga group (p= 0.018, 0.042, 0.049, 0.05 respectively). The reported cases of eclampsia, CPD, PROM, and EMCS, while improved, were not statistically significant (p=0.157, 0.317, 0.919 and 0.617, respectively). Conclusion: Yoga is effective in management of some pregnancy complications in high-risk pregnancies and can improve pregnancy outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 14.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- Female
入选标准
- •Pregnant women within 8 to 12 weeks of pregnancy and with any of the following risk factors were considered qualified for the study: Bad obstetrics history Twin pregnancies Maternal age between 14 and 20 or between 35 and 45 Obesity (BMI greater than 30) History of pregnancy complications among blood relatives: sister, mother, or grandmother.
排除标准
- •Qualified subjects with any of the following disorders were excluded from the study: Severe renal, hepatic or gallbladder, or heart disease.
- •Structural abnormalities in the reproductive system.
- •Hereditary anemia (such as sickle cell disease) or hemoglobin S-C disease, Seizure disorders.
- •Taking chemotherapy drugs.
- •Having sexually transmitted diseases including syphilis and HIV infection.
- •Having any medical conditions that prevent them from safely and effectively practicing the interventions (e.g. spinal deformities or any DSM-IV type I axis psychiatric condition).
结局指标
主要结局
Maternal Blood Pressure
时间窗: 12th week, 20th week, and 28th week gestation
Protein in urine, Platelet count, blood uric acid, Doppler parameters, stress instruments, and Blood markers: TNF-alpha;, IL-6, IL-10, sFlt-1, E-selectin, endoglin, and adiponectin
时间窗: 12th week, 20th week, and 28th week gestation
次要结局
- Measure of stress:Objectively: Heart Rate Variability (HRV) and subjectively: Perceived Stress Scale (PSS)(13th week, 20th week, 28th week gestation)