Pharmacist Intervention Programme in Secondary Care to Improve Medication Adherence in Patients With Hypertension
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 532
- 试验地点
- 1
- 主要终点
- Percent of patients that are at least 80% adherent (Medication possession rate > 0.8) to antihypertensives and statins
研究概览
简要总结
Patients with hypertension have an increased risk of stroke and myocardial infarction. However, poor adherence to treatment with antihypertensives and lipid-lowering agents occurs frequently within this patient group. The purpose of this study is to investigate whether a complex tailored intervention in a hospital setting will lead to increased medication adherence and fewer cardiovascular events when compared to a usual care group. Interventions focus on motivational interviewing, medication review and telephone follow up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: 18 years or older
- •Patients receiving ambulatory treatment for hypertension in a hospital setting
- •The patient or a carer usually dispenses the patient's medications
- •Patient lives in the Southern Region of Denmark
- •Written consent
排除标准
- •Lives in a care home or institution
- •Receive dose dispensed medicine from a pharmacy
- •Medicine is dispensed by a nurse in the patient's home
- •Correctional mental health patients
研究组 & 干预措施
Usual care
Usual care
干预措施: Usual care (Behavioral)
Complex tailored intervention
The interventions consists of 3 elements:
- Medication review with recommendations focused on antihypertensives and statins and adherence to guidelines and patient´s adherence to medications
- Consultation with a pharmacist using motivational interviewing techniques
- Follow-up telephone calls one month and six months after inclusion
干预措施: Complex tailored intervention (Behavioral)
结局指标
主要结局
Percent of patients that are at least 80% adherent (Medication possession rate > 0.8) to antihypertensives and statins
时间窗: One year from inclusion
次要结局
- Non-persistence with antihypertensives and statins measured by percent of patients that are not supplied with medications for more than three continuous months(One year from inclusion)
- Reduction in systolic and diastolic blood pressure(One year from inclusion)
- Composite endpoint (stroke, myocardial infarction or cardiovascular death)(One year from inclusion)
研究者
Ulla Hedegaard
PhD student, MSc (pharm), Odense University Hospital
Odense University Hospital