NCT06800677进行中（未招募）不适用
Methylated Biomarkers Predictive of Endometrial Cancer Risk
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Sensitivity, specificity, negative and positive predictive value of single gene methylation classifiers in predicting the presence of endometrial cancer in minimally- and invasive samples
研究概览
简要总结
The goal of this observational study is to identify endometrial cancer risk predictive biomarkers and to optimise the methodology for their detection and quantification in non-invasive samples.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women aged 45-70 years
- •Attending St Mary's Hospital, Manchester for an elective hysterectomy by any route for either the treatment of endometrial cancer or a benign gynaecological condition
- •Able to consent to participation in the study
排除标准
- •Presence of malignancy asides from endometrial cancer
- •Undergoing elective hysterectomy for suspected ovarian cancer
结局指标
主要结局
Sensitivity, specificity, negative and positive predictive value of single gene methylation classifiers in predicting the presence of endometrial cancer in minimally- and invasive samples
时间窗: 1 day
次要结局
- Sensitivity, specificity, positive and negative predictive value of a multi-gene methylation classifier for predicting the presence of endometrial cancer(1 day)
研究者
Sarah Kitson
Clinical Lecturer
University of Manchester
研究点 (1)
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