A Prospective Study of Cardiovascular Risk of Patients Admitted for Acute Exacerbation of COPD
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 150
- 主要终点
- Percentage of patients observed to have different high-risk factors for future COPD exacerbation
研究概览
简要总结
This is a prospective study to assess the burden of existing or hidden cardiovascular (CV) and renal disease in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in a Hong Kong public hospital setting. By implementing a chronic obstructive pulmonary disease (COPD) discharge care bundle with integrated CV/renal screening, the study aims to quantify undiscovered disease prevalence, evaluate risk factors for future exacerbations, and compare re-admission rates against historical controls, ultimately informing integrated cardiopulmonary management strategies.
详细描述
Chronic obstructive pulmonary disease (COPD) is a major global health concern, characterized by persistent respiratory symptoms and airflow limitation, and it frequently coexists with cardiovascular disease (CVD), which significantly contributes to morbidity and mortality in this population.
This is a prospective study to assess the burden of existing or hidden cardiovascular (CV) and renal disease in patients with acute exacerbation of COPD (AECOPD) in a Hong Kong public hospital setting. By implementing a COPD discharge care bundle with integrated CV/renal screening, the study aims to quantify undiscovered disease prevalence, evaluate risk factors for future exacerbations, and compare re-admission rates against historical controls, ultimately informing integrated cardiopulmonary management strategies.
The objectives and hypotheses are as follows:
Objectives and Hypotheses Primary Objective To describe the prevalence of undiscovered cardiovascular and renal disease burden among patients hospitalized for AECOPD in a Hong Kong public clinical setting.
• Hypothesis: A significant proportion of AECOPD patients will have previously undiagnosed CV or renal diseases identified through proactive screening, highlighting the need for routine assessments.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥40 years
- •Patients hospitalized due to COPD exacerbation.
- •Patients diagnosed with COPD, a confirmed COPD diagnosis with a specific FEV1/FVC ratio (<0.70)
- •Able to provide informed consent
排除标准
- •Pregnant subjects
- •Inability to give informed consent
- •Cancer patient who are on active chemotherapy or on palliative care
研究组 & 干预措施
Prospective recruitment with implementation of the COPD discharge care bundle.
implementation of the COPD discharge care bundle
干预措施: implementation of the COPD discharge care bundle. (Other)
结局指标
主要结局
Percentage of patients observed to have different high-risk factors for future COPD exacerbation
时间窗: 12 months
Percentage of patients observed to have different high-risk factors for future COPD exacerbation
次要结局
- Re-admission rate(12 months)
- Major Adverse Cardiac Events (MACE)(12 months)
研究者
Fanny W.S. Ko
Honorary clinical professor
Chinese University of Hong Kong