Accidental Reactions in a French Cohort of Children With Peanut and/or Tree Nut Allergy.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 147
- 试验地点
- 1
- 主要终点
- the number of episode of allergic reactions in real life
研究概览
简要总结
Food allergy is an immune reaction, triggered by food protein allergens, of varying severity, from mild local reaction to life threatening anaphylaxis and fatalities.
Peanut is a plant from the botanical family of the Fabaceae, more commonly known as legumes. The prevalence of peanut and tree nut allergy is increasing. In France (ELFE cohort), it is estimated to 0.93%. The tree nuts include mainly almond, hazelnut, pistachio, cashew nut, walnut, pecan nut and Brazil nut. Allergy's prevalence is estimated to 0.54% in children up to 5.5 years. Peanut allergy is a main cause of anaphylaxis and deaths due to food allergy.
Recurrence of food allergy is a main concern. The risk has been estimated to 10% per year for peanut.
In France, Data in real-life on the rate of recurrence of allergic reactions and anaphylaxis to peanut/tree-nut as well as risk factors, are lacking.
The objective of this study is to assess the frequency of allergic reaction to peanut and tree-nuts, to describe the reactions' characteristics and risk factors.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed allergy to peanuts and/or nuts
排除标准
- •Other chronic diseases, except allergic comorbidities (asthma, rhinitis, atopic dermatitis, other food allergy)
结局指标
主要结局
the number of episode of allergic reactions in real life
时间窗: At 1 year
次要结局
- the severity of the allergic reactions according to a validated scale (FASS scale)(At 1 year)
- interview for the characteristics of the allergic reactions(At 1 year)
- interview to defined the risks factor associated(At 1 year)