Use of Chlorhexidine-gel-Impregnated Dressing Compared to Transparent Polyurethane Film Dressing as Coverage of the Site of Insertion of Central Venous Catheter, in the Evaluation of Catheter Colonization in Critically Ill Adults Patients: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- Catheter Colonization
研究概览
简要总结
The purpose of this study is to compare the use of chlorhexidine-gel-impregnated dressing and the transparent polyurethane film dressing as coverage of the site of insertion of central venous catheter, in the evaluation of catheter colonization in critically ill adults patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Critically ill patients hospitalized carrying a short-term central venous catheter
排除标准
- •Use of a central venous catheter with antimicrobial coating
- •Suspected or confirmed bacterial infection at randomization
- •Known allergic/hypersensitivity reaction to any compounds of the treatment
- •Active lesions in the skin where the CVC is located and / or where the dressing of CVC is being conducted;
结局指标
主要结局
Catheter Colonization
时间窗: Participants will be followed from placement until the withdraw of the central venous catheter, an expected average of 3 weeks.
With aseptic technique, the central venous catheter will be withdrawn and a 5 centimeters distal portion of the catheter will be cut and conditioned in sterile test tube and sent to the microbiology laboratory. It will be considered a Catheter Colonization a significant growth of one or more microorganism in a semiquantitative culture of the catheter tip. It is according to the Clinical Practice Guidelines for the Diagnosis and management of Intravascular Catheter- Related Infection: 2009 Update by the Infectious Diseases Society of America
次要结局
- Clinical Exit Site Infection(Participants will be followed from placement until the withdraw of central venous catheter, an expected average of 3 weeks)
- Microbiological Exit site Infection(Participants will be followed from placement until the withdraw of central venous catheter, an expected average of 3 weeks)
研究者
Amanda Salles Margatho
PhD Student
University of Sao Paulo