NL-OMON45239已完成4 期
Optimising adalimumab treatment in psoriasis with concomitant methotrexate. - OPTIMAP study
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •In order to be eligible to participate in this study, a subject must meet all of the following criteria:;*Have a diagnosis of moderate to severe plaque psoriasis (PASI*8 at time of screening);
- •*Is a candidate for the treatment with biologic drugs according to the pertaining guidelines (NVDV 2011);
- •*Willing and able to use adequate contraceptives during the study (all men and pre-menopausal women);
- •*Adalimumab therapy will be started for the treatment of psoriasis
- •*Signed informed consent.
排除标准
- •*History of significant MTX or adalimumab toxicity, intolerability or contraindication
- •*Prior treatment with adalimumab
- •*Age < 18 years;
- •*Pregnant and nursing women.
- •*other immunosuppressive medication (prednisone, mycofenolaatmofetyl (Cellcept e.g.), ciclosporine (Neoral e.g.), sirolimus (Rapamune), systemic tacrolimus (Prograft e.g.) e.g.)
研究者
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