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临床试验/NCT04684433
NCT04684433已完成不适用

Surgery in the Time of COVID-19 Pandemic

Brugmann University Hospital4 个研究点 分布在 1 个国家目标入组 707 人开始时间: 2020年4月14日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
707
试验地点
4
主要终点
Intensive care unit stay (in days)

研究概览

简要总结

The ongoing coronavirus disease 2019 (COVID-19) which started in China, was declared on the 11th of March as a global pandemic 2020 by the World Health Organization (WHO).

Governments around the world have introduced differing forms of lock downs since the start of the pandemic demanding citizens to confine to their homes and go out only in necessity to minimize exposure to the virus. The response was observed in the emergency departments and the number of patients who presented for non-Covid issues drastically reduced.

Hospitals activated their mass casualty management plans and have reorganized and overstretched their capacity to be able to absorb both the influx of patients with the virus and those with other conditions.

Part of that reorganization was reducing the surgical activity. The main focus was shifted to patients who are considered urgent and elective surgery were postponed. Hence only surgical emergencies were maintained. Many did not present to the emergency department for fear to contract the virus and from a sense of national and global solidarity against that pandemic.

Whereas these measures are essential to prevent the spread of the virus, it may be hypothesized that for non-Covid issues, including surgical emergencies, patients may present late to the emergency department due to fear of contracting the infection in hospital. This would delay their management and lead to a worsened symptomology on presentation requiring a more complex surgical intervention with an increased complication profile.

The investigators present initial data from four major hospitals in Belgium, characterizing surgical emergencies that were managed since the start of the pandemic and discuss the repercussion the pandemic has on management of urgent surgical patients and most likely evolution of surgery after the pandemic.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Patients who had a surgical procedure since the start of the lock down in Belgium due to the COVID19 pandemic (16 of March 2020 to the 12 of April 2020).

排除标准

  • 未提供

结局指标

主要结局

Intensive care unit stay (in days)

时间窗: 5 minutes

Intensive care unit stay (in days)

Surgery code

时间窗: 5 minutes

Type of surgery as defined by the surgery code

Delay between surgery and first symptoms

时间窗: 5 minutes

Delay between surgery and first symptoms

Surgery duration

时间窗: 5 minutes

Surgery duration (anesthesia included)

Covid status post-surgery

时间窗: 5 minutes

Covid status post-op (positive=1, negative=0 )

COVID19 Diagnosis by CT scan

时间窗: 5 minutes

COVID19 Diagnosis confirmed by CT scan of the thorax (Yes=1, No=0)

COVID19 symptoms - myalgia

时间窗: 5 minutes

myalgia (Yes=1, No=0)

COVID19 symptoms -respiratory distress

时间窗: 5 minutes

respiratory distress (Yes=1, No=0)

Treatment for COVID19 - Plaquenil

时间窗: 5 minutes

Plaquenil (Yes=1, No=0)

Covid status before surgery

时间窗: 5 minutes

Covid status before surgery (positive=1, negative=0 )

COVID19 Diagnosis by swab test

时间窗: 5 minutes

COVID19 Diagnosis by swab test (Yes=1, No=0)

Treatment for COVID19 - Antivirals

时间窗: 5 minutes

Antivirals (Yes=1, No=0)

Need for intubation

时间窗: 5 minutes

Need for intubation (Yes=1, No=0)

Death

时间窗: 5 minutes

Mortality (Yes=1, No=0)

Urgency

时间窗: 5 minutes

Degree of urgency of the surgery

COVID19 symptoms - dry cough

时间窗: 5 minutes

dry cough (Yes=1, No=0)

COVID19 symptoms - fever

时间窗: 5 minutes

fever (Yes=1, No=0)

COVID19 symptoms - anosmia

时间窗: 5 minutes

anosmia (Yes=1, No=0)

Post-op complications

时间窗: 5 minutes

Post-op complications

COVID 19 Diagnosis by antibody test

时间窗: 5 minutes

COVID 19 Diagnosis by antibody test (Yes=1, No=0)

Type of anesthesia

时间窗: 5 minutes

Type of anesthesia

Hospital stay (in days)

时间窗: 5 minutes

Hospital stay (in days)

次要结局

  • Gender(5 minutes)
  • Age(5 minutes)
  • BMI(5 minutes)
  • Ethnicity(5 minutes)
  • Comorbidities(5 minutes)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Pierre Wauthy

Medical Director

Brugmann University Hospital

研究点 (4)

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