Center for Inherited Muscle Research Neuromuscular Research Biobank
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- To collect, store, and share with other researchers any tissues that subjects with all types of neuromuscular disease are willing to donate.
研究概览
简要总结
The purpose of this research repository is to collect, store, and share with other researchers any tissues that subjects with all types of neuromuscular disease are willing to donate. These samples will be stored at Virginia Commonwealth University (VCU) and will be used for future research with this population.
详细描述
The study involves collection of medical information about research participants and their families. No identifying information about family members will be collected. Research participants will be asked for any general knowledge they have related to possible neurological disorders.
Research participants are also given the opportunity to provide blood, skin cells, urine, saliva, fecal matter, muscle tissue, cells, DNA and/or RNA samples.
Before any study procedures take place, the informed consent form will be provided and reviewed with potential research participants in detail. Potential research participants will have an opportunity to ask additional questions before starting any study procedures.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- — 至 75 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Willing and able to give informed consent
- •Positive diagnosis or suspected diagnosis of neuromuscular disease, or
- •Family history of neuromuscular disease, or
- •Healthy volunteer
- •Age Neonates-75
排除标准
- •Unwilling to sign consent
结局指标
主要结局
To collect, store, and share with other researchers any tissues that subjects with all types of neuromuscular disease are willing to donate.
时间窗: Baseline
Subjects will have the opportunity to provide the following samples: saliva or cheek swab, urine sample (up to 15ml), feces (up to 2mg of a stool sample), blood (up to 40ml), muscle biopsy tissue, and cell line (subjects have the option to allow a cell line to be made from their blood, muscle, or skin biopsies to provide a renewable supply of DNA and other cell components for research)
次要结局
- To collect medical history information from subjects with all types of neuromuscular disease and healthy controls.(Baseline)