NCT07492147招募中不适用
Impact of Negative Pressure Suction on Irrigation Fluid Absorption and Postoperative Infection Risk During Flexible Ureteroscopic Lithotripsy: A Prospective Cohort Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- Volume of irrigation fluid absorbed
研究概览
简要总结
The goal of this observational study is to learn about the effects of using negative pressure suction during retrograde intrarenal surgery (RIRS) in patients aged 18 and older with kidney stones. The main questions it aims to answer are:
- Does using negative pressure suction during surgery affect the amount of irrigation fluid absorbed by the patient's body?
- Does using negative pressure suction reduce the risk of postoperative infections, such as fever, systemic inflammatory response syndrome (SIRS), and urosepsis? Researchers will compare patients who undergo surgery with a negative pressure suction sheath to patients who undergo surgery with a standard sheath (without suction) to see if the suction technology reduces fluid absorption and lowers the risk of postoperative complications.
Participants will undergo their scheduled kidney stone surgery as part of their regular medical care. Researchers will collect their routine clinical data from the hospital system, including:
- Preoperative test results (such as CT scans, ultrasounds, and urine tests).
- Intraoperative data (such as surgery duration and the exact amount of fluid absorbed, measured by a monitoring device).
- Postoperative recovery data (such as body temperature, pain levels, hospital stay length, and any signs of infection).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 years and older with kidney stones who meet the surgical indications for RIRS;
- •Patients who have provided informed consent.
排除标准
- •Concurrent combination with other surgical procedures, such as percutaneous nephrolithotomy (PCNL);
- •Patients with malignancies, urinary tuberculosis, immune system diseases, or hyperthyroidism;
- •Congenital renal anomalies, such as polycystic kidney disease or horseshoe kidney;
- •Presence of untreated urinary tract infections;
- •Inability to tolerate surgery due to severe cardiopulmonary dysfunction, hepatic or renal insufficiency, or coagulation abnormalities.
结局指标
主要结局
Volume of irrigation fluid absorbed
时间窗: Intraoperative (During the surgery)
次要结局
- Incidence of postoperative fever and infectious complication(Up to 7 days postoperatively)
- ostoperative length of hospital stay(From surgery to hospital discharge (an average of 3-7 days))
- Stone-free rate (SFR)(1 month postoperatively)
研究者
Zhiping Wang
Professor; Chief Physician
Lanzhou University Second Hospital
研究点 (1)
Loading locations...
相似试验
尚未招募
1/2 期
Comparing different ways of cleaning the viscoelastic substance from the eyes of patients during cataract surgery to improve the safety and recovery of patients admitted for cataract surgeryCTRI/2025/11/097990SUNKARA VENKATA MAHALAKSHMI126
尚未招募
2 期
Comparative analysis of applying negative pressure to pleural suction through intercostal drainage tube versus not applying negative pressure for intercostal drainage tube to analyze duration of intercostal tube drainageCTRI/2025/08/09357390
尚未招募
2/3 期
Evaluation of pain after single visit root canal treatment using different temperatures and concentrations of disinfecting solution.CTRI/2025/03/082769SGT Dental College90
已完成
不适用
The Effect of Different Irrigation Methods Used During Endodontic Treatment on Postoperative Pain in Teeth With Periapical LesionsNCT07410832Akdeniz University88
尚未招募
不适用
A Study Comparing Two Irrigation Methods Used in Root Canal Treatment of Baby TeethCTRI/2025/07/091867GOVINDARAJAA V K70
