Stroke Volume Versus Inferior Vena Cava Collapsibility Index to Predict Postinduction Hypotension in Intestinal Obstruction
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 75
- 主要终点
- Efficacy of SV versus IVC-CI as Predictors for Post-Induction Hypotension Efficacy of SV versus IVC-CI as Predictors for Post-Induction Hypotension
研究概览
简要总结
Postinduction hypotension (PIH) is a frequent complication during general anesthesia. This study aims to compare the predictive effectiveness and diagnostic accuracy of stroke volume (SV) measured via left ventricular outflow tract velocity time integral (LVOT-VTI) versus the inferior vena cava collapsibility index (IVC-CI) using transthoracic echocardiography. The assessment will be conducted in adult patients with intestinal obstruction undergoing exploratory abdominal surgery under general anesthesia.
详细描述
Postinduction hypotension (PIH) is associated with adverse postoperative outcomes. In this diagnostic accuracy observational study, adult patients aged 40-70 years with intestinal obstruction undergoing exploratory abdominal surgery under general anesthesia will be enrolled at Ain Shams University Hospitals. Prior to induction of general anesthesia, transthoracic echocardiography (TTE) will be performed to measure the stroke volume (SV) via LVOT-VTI and the inferior vena cava collapsibility index (IVC-CI). Patients will receive standard rapid sequence induction, and hemodynamic parameters will be monitored post-induction to evaluate the predictive value, sensitivity, and specificity of SV versus IVC-CI for postinduction hypotension. Secondary outcomes including incidence of PIH, length of hospital stay, PACU recovery time, and postoperative nausea and vomiting will also be recorded.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients with intestinal bowel obstruction undergoing exploratory abdominal surgery under general anesthesia.
- •Age 40 to 70 years old.
- •Body Mass Index (BMI) = 18 to 25 kg/m
- •American Society of Anesthesiologists (ASA) physical status grade I or II.
排除标准
- •American Society of Anesthesiologists (ASA) physical status grade >= III.
- •Patients in whom the IVC cannot be visualized or patients with poor echogenicity.
- •Patients with hemodynamic instability.
- •Patients with vascular, respiratory, or cardiac diseases (e.g., cardiomyopathy, heart valve disease, arrhythmia, or bad exercise tolerance).
- •Pregnant patients.
- •Difficult airway or multiple intubatio
结局指标
主要结局
Efficacy of SV versus IVC-CI as Predictors for Post-Induction Hypotension Efficacy of SV versus IVC-CI as Predictors for Post-Induction Hypotension
时间窗: Measured baseline pre-induction and compared immediately post-induction.
Comparison of the effectiveness and diagnostic accuracy (AUC) of stroke volume (SV) measured via LVOT-VTI versus inferior vena cava collapsibility index (IVC-CI) measured via TTE in predicting post-induction hypotension. Comparison of the effectiveness and diagnostic accuracy (AUC) of stroke volume (SV) measured via LVOT-VTI versus inferior vena cava collapsibility index (IVC-CI) measured via TTE in predicting post-induction hypotension.
Diagnostic accuracy of Stroke Volume (SV) to predict post-induction hypotension.
时间窗: Baseline (pre-induction) and immediately post-induction.
Area under the receiver operating characteristic curve (AUC) of stroke volume measured via left ventricular outflow tract velocity-time integral (LVOT-VTI) as a predictor of post-induction hypotension.
Diagnostic accuracy of Inferior Vena Cava Collapsibility Index (IVC-CI) to predict post-induction hypotension.
时间窗: Baseline (pre-induction) and immediately post-induction.
Area under the receiver operating characteristic curve (AUC) of inferior vena cava collapsibility index measured via transthoracic echocardiography (TTE) as a predictor of post-induction hypotension.
次要结局
- Incidence of Post-Induction Hypotension Incidence of Post-Induction Hypotension(Within 3 minutes following induction of general anesthesia.)
- Length of Hospital Stay Length of Hospital Stay(From date of surgery until hospital discharge (up to 9 months).)
- Time to Recovery from Post-Anesthesia Care Unit (PACU) Time to Recovery from Post-Anesthesia Care Unit (PACU)(Intraoperative / immediate postoperative period until PACU discharge (up to 24 hours).)
- Incidence of Post-Induction Hypotension(Within 3 minutes following induction of general anesthesia.)