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临床试验/NCT06448520
NCT06448520招募中不适用

Reference Values for the Muscle Power Sprint Test in Children Aged 5-12 Years

Erasmus Medical Center2 个研究点 分布在 1 个国家目标入组 480 人开始时间: 2024年12月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
480
试验地点
2
主要终点
Reference values for the MPST for children aged 5-12 years, both male and female.

研究概览

简要总结

The goal of this prospective, cross-sectional study is to develop updated reference values for the Muscle Power Sprint Test (MPST) in children aged 5-12 years.

The main question it aims to answer is:

• What are reference ('normal') values for the MPST in children aged 5-12 years?

Participants will be asked to perform six short sprints of fifteen meters each, with a ten-second rest between each effort.

详细描述

SUMMARY Rationale: Children with congenital abnormalities face risks of below-average lung function and exercise tolerance (1-3). As the standard of care, our tertiary hospital enrolls these children in a prospective, longitudinal follow-up program from birth (4). This program involves regular assessments of overall health and development, including spirometry and exercise tolerance tests conducted by pediatric physiotherapists. Historically, the Bruce treadmill protocol was employed for testing maximal exercise tolerance in children aged 4 and above, but it presented limitations such as high muscular demands of the steep inclines and large workload increments, impacting reliability and potentially causing premature discontinuation (5).

In response, the Bruce protocol was replaced in newer follow-up program versions by the Muscle Power Sprint Test (MPST). Unlike the Bruce protocol, which assesses aerobic capacity, the MPST focuses on anaerobic exercise capacity, which is crucial for children's daily activities like playing with peers (6). Performing the MPST involves six short runs of 15 meters, from which the calculated 'mean power' serves as the primary outcome. The distance covered during these runs corresponds well to the distances children cover during daily play activities.

While Dutch norm values for children aged 6-18 exist, gathered mainly in rural areas between 2012 and 2016, the study highlights the need for updated reference values. Lifestyle changes, exacerbated by the Covid-19 pandemic, underscore the urgency of updating exercise tolerance reference values (7). Notably, there is a current lack of established reference values for 5-year-olds undergoing MPST testing in our longitudinal follow-up program, emphasizing the need for comparative data in this age group.

Objective: Our primary goal is to establish reference values for the MPST for primary school children aged 5-12 belonging to a diverse population living in the Netherlands.

Study design: The study adopts a prospective cross-sectional design.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
5 Years 至 12 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Age 5-12 years
  • Attending primary education at one of the participating schools or attending participating after-school childcare centers.

排除标准

  • Contra-indication for maximal exercise due to cardiac or respiratory morbidities
  • Injuries limiting maximal exercise capacity
  • Known with motor function impairment which may hamper maximal exercise (e.g. neurologic comorbidities)

结局指标

主要结局

Reference values for the MPST for children aged 5-12 years, both male and female.

时间窗: Data gathering: 6 months, data processing: 6 months.

Reference values for the MPST for children aged 5-12 years, both male and female.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Louis Dossche

MD, PhD Candidate

Erasmus Medical Center

研究点 (2)

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