NCT01747122已完成不适用
A Randomised Trial of Peri-operative Nerve Block and Continuous Infusion of Local Anaesthetic Via Wound Catheter Versus Epidural in Patients Undergoing Open Liver Resection.
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 97
- 试验地点
- 1
- 主要终点
- Length of stay
研究概览
简要总结
The investigators plan to compare epidurals versus wound catheters for effects on pain relief and recovery following open liver surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing open hepatic resection for benign or malignant conditions.
排除标准
- •Patients with contraindication to either epidural or wound catheter techniques.
- •Inability to give written, informed consent.
- •Jaundice (Bilirubin > 100 μmol/L)
- •Liver resection combined with secondary surgical procedure.
- •Age < 18 years
- •Pregnant women
- •patients on long term opiates for chronic pain
研究组 & 干预措施
Wound catheter
Experimental
Wound catheter
干预措施: Wound catheter (Device)
Epidural
Active Comparator
Standard epidural, pre-operative insertion, to be run for 48 hours
干预措施: Epidural (Device)
结局指标
主要结局
Length of stay
时间窗: Measurement made on day of discharge which is expected to be on average bewteen 5 and 10 days after surgery.
Number of days (to nearest half day) patients stay in hospital.
次要结局
- Central Venous Pressure(During liver transection)
- Molecular response to surgery(Days 0, 1 and 3)
- Operative field asessment(During liver transection)
- Estimated Blood Loss(Intra-operative)
- Pain Scores(Performed daily at 0900 hours. On the day of surgery pain scores will be performed at 2, 6 and 12 hours post surgery.)
- Pringle time(Intra-operative)
研究者
研究点 (1)
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