NCT07655596尚未招募4 期
Continuous Infusion Versus Intermittent IV Bolus of Cefazolin: Prevention of Surgical Site Infection During Orthopedic Surgeries in Egyptian Patients.
干预措施
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 100
研究概览
简要总结
A randomized controlled trial on adults who underwent orthopedic surgery. To evaluate the effectiveness of intraoperative continuous infusion (CI) of cefazolin compared with intermittent (INT) cefazolin administration in preventing SSIs in the orthopedic surgical population.
Eligible patients will be randomized in a block design into 2 groups: intervention and control. The intervention group will use continuous infusion of cefazolin (CI), while the control group will follow the traditional presurgical prophylaxis protocol of intermittent cefazolin doses (INT).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Orthopaedic surgical ward patients who underwent major surgery.
排除标准
- •Patients who require reoperation within 30 days.
- •Immunosuppressant patients.
- •Patients who are not adherent to the protocol time or dosing, either preoperatively, during, or postoperatively.
- •Pregnancy or breastfeeding.
研究组 & 干预措施
Continuous infusion of cefazolin
Experimental
干预措施: Cefazolin 2 g Infusion (Drug)
Intermittent cefazolin injection
Active Comparator
干预措施: Cefazolin 2 GM Injection (Drug)
研究者
Hebatallah Ali Abdeen
Principal Investigator
Helwan University
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