NL-OMON55881已完成不适用
Validation of bi-dimensional (2D) and three-dimensional (3D) Fourier Decomposition (FD) as Magnetic Resonance Imaging (MRI) technique to assess lung ventilation and perfusion compared to computed tomography (CT), Hyperpolarised gases (HP-MRI) and Contrast-Enhanced MRI (CE-MRI) - VIPS MRI
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 19
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 2 至 99(—)
入选标准
- •CF patients
- •Diagnosed with CF with sweat and genetic testing
- •Age between 10-18 years
- •Scheduled for biennial CT scan
- •Willing and capable to perform spirometer controlled chest MRI
- •Informed consent
- •Healthy Volunteers
- •Age 10-18 years
- •Willing and capable to perform spirometer controlled chest MRI
- •Informed consent
- •Healthy volunteers (MRI standardization)
- •Age 18 years and older
- •Willing and capable to perform chest MRI
- •Informed consent
排除标准
- •MRI contraindication (i.e. cardiac pacemaker, metallic implant, hearing aids,
- •Claustrophobic
- •Pregnancy
- •Not willing or unable to perform MRI
- •CF Patients
- •Recent (< 1 month) RTE with use of i.v. antibiotics
- •Chronic oxygen therapy
- •Any other severe comorbidities that could limit imaging
- •Healthy volunteers
- •Recent (< 1 month) history of lung disease (i.e. pneumonia)
- •Known history of chronic lung disease (i.e. asthma)
- •Known history of congenital lung disease (i.e. bronchopulmonary dysplasia,
- •tracheomalacia)
研究者
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