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临床试验/NCT05273853
NCT05273853Unknown不适用

Speech Outcome After Partial Adenoidectomy in Patients With Risk of Hypernasality

Sohag University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2022年2月4日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
30
试验地点
1
主要终点
Speech Outcome

研究概览

简要总结

Adenoid hypertrophy is a common cause of airway obstruction in children; it may lead to mouth breathing, nasal discharge, snoring, sleep apnea, and hyponasal speech.

详细描述

Adenoid hypertrophy is a common cause of airway obstruction in children; it may lead to mouth breathing, nasal discharge, snoring, sleep apnea, and hyponasal speech. It also contributes to the pathogenesis of rhinosinusitis and recurrent otitis media. However, the adenoid lies in the posterior nasopharyngeal wall and may act as a pad against the palate facilitating velopharyngeal closure, especially in patients with palatal abnormalities; Its presence can compensate for a short or poorly mobile palate. Following adenoidectomy, compensation is eliminated and velopharyngeal insufficiency (VPI) may result. Therefore, patients with palatal abnormalities (such as poor palatal mobility, short palate, occult submucosal cleft palate, scarred palate after previous tonsillectomy, and repaired cleft palate) are at high risk to develop hypernasality after complete adenoidectomy, and in such situations conservative or partial adenoidectomy is performed

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
1 Year 至 12 Years(Child)
性别
All
接受健康志愿者
否

入选标准

  • •Patient with symptoms of adenoid hypertrophy.
  • •High risk to VPI:
  • •Short palate.
  • •Scarred palate after previous tonsillectomy.
  • •Occult submucous cleft.
  • •Deep pharynx.
  • •Repaired cleft palate.

排除标准

  • •Any neurological deficit, muscular disorder or structural defects of the palate (as cleft palate).

研究组 & 干预措施

Patients with high risk of hypernasality

Other

In 1958, Gibb indicated an incidence of hypernasality (escape of air from nose as in patients with cleft palate) postadenoidectomy in approximately 1of 2000 cases. Closure pattern of velopharyngeal valve in children is veloadenoidal rather than velopharyngeal closure. Adenoid tissue is vital to velopharyngeal closure in children and its removal necessitates a change in the closure pattern of velopharyngeal valving. These changes are easily overcome if there is no anatomic abnormality

干预措施: Partial Adenoidectomy (Procedure)

结局指标

主要结局

Speech Outcome

时间窗: 3 months after operation

Change of a degree of Nasal Tone during speech

Speech Outcome

时间窗: 1 month after operation

Change of a degree of Nasal Tone during speech

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dina Awida Hasb Allah

Resident of Otolaryngology

Sohag University

研究点 (1)

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