Study of Obesity Control by Astragalus and Notoginseng Extrats
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 主要终点
- The changes of body weight and BMI of the subjects.
研究概览
简要总结
The effects of the Astragalus and Notoginseng extrats on obesity control was demonstrated in a randomized double-blind, and crossover human trial.
详细描述
Obesity refers to the body due to physiological or biochemical function of the change caused by excessive accumulation of body fat, resulting in weight gain. Hence, the aim of this study was to evaluate the effects of the Astragalus and Notoginseng extrats on obesity control by a randomized double-blind and crossover human trial. Subjects with simple obesity (body mass index (BMI) ≥ 27 or body fat ≥ 30%) ingested 5 extrats (n = 19) capsules or placebo (n = 19) perday for 12 weeks of a stage. Anthropometric measurements (body weight, body fat, blood pressure) and blood biochemical markers including fasting blood glucose (FBG), albumin, total cholesterol (TC), triglyceride (TG), HDL-C, LDL-C, creatinine (Cr), blood urea nitrogen (BUN), AST, ALT were examined every six weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Body mass index (BMI) ≥ 27 or body fat ≥ 30%;
- •No history of serious diseases associated with heart, liver, kidney, endocrine systems or other organs;
- •No drugs consumption.
排除标准
- •BMI >35;
- •Alcoholic;
- •US-controlled diabetics;
- •Stoke in past one year;
- •High blood pressure;
- •Mental diseases or melancholia;
- •Pregency or breast-feeding a child.
结局指标
主要结局
The changes of body weight and BMI of the subjects.
时间窗: 12 weeks
values change of body weight and BMI between before to after 12 weeks
次要结局
- The changes of triglyceride (TG) of the subjects(12 weeks)
研究者
You-Cheng Shen
School of Health Diet and Industry Managment
Chung Shan Medical University