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临床试验/NCT02869269
NCT02869269已完成不适用

A Study of Circulating Immune Cell Activity Changes in Blood of Colorectal Cancer Patients

Konkuk University Medical Center1 个研究点 分布在 1 个国家目标入组 67 人开始时间: 2015年10月最近更新:
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适应症

试验速览

阶段
不适用
状态
已完成
入组人数
67
试验地点
1
主要终点
Circulating helper T cell activity
研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Previous studies have shown that colorectal cancer patients' prognosis and overall survival was related with immune cell expression in patients' tissue. However, the circulating immune cell activity changes in patients' blood has few studies. The purpose of this study is to analyze the variation of circulating immune cell activity in colorectal patients' blood which is classed as clinical staging.

详细描述

The patients were classed as clinical staging

  1. Early (stage1+2) and Late(stage3+4)
  2. regional lymph node metastasis
  3. Distant metastasis
  4. TNM stage

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
20 Years 至 —（Adult, Older Adult）
性别
All
接受健康志愿者
否

入选标准

  • •patient who was planned to undergo colorectal cancer surgery.

排除标准

  • •age < 20 years old
  • •history of hypersensitivity reaction in propofol or sevoflurane
  • •history of previous cancer
  • •patient with ongoing inflammation

结局指标

主要结局

Circulating helper T cell activity

时间窗: preoperative time

change of expression level of T cell (0\~100 %)

次要结局

  • Cytotoxic T cell and natural killer cell activity(preoperative time)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Seong-Hyop Kim

Associate professor

Konkuk University Medical Center

研究点 (1)

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