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临床试验/NCT04464343
NCT04464343已完成不适用

The Biomechanical Mechanism for Gait and Plantar Pressure Changes After Posterior Cruciate Ligament Rupture and Reconstruction

Peking University Third Hospital1 个研究点 分布在 1 个国家目标入组 110 人开始时间: 2014年6月14日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
110
试验地点
1
主要终点
walking speed

研究概览

简要总结

Investigating the biomechanics for the PCL ruptured or reconstructed patients during walking, jogging, cutting, jumping. To establish a knee joint biomechanical evaluation model to quantify and evaluate the plantar pressure information under dynamic load-bearing state after PCL fracture. Provide a precise basis for the biomechanical state of the knee, and establish a clinically practical automatic analysis of plantar pressure information and an expert diagnostic system.

详细描述

Background: The posterior cruciate ligament (PCL) is an essential structure in knee stabilization. Knee cartilage degeneration after a PCL injury has been reported in several studies. Understanding the changes in movement patterns of patients with PCL ruptures could help clinicians make specific treatment protocols to restore patients' sporting ability and prevent joint degeneration. However, the kinematics and kinetics of the lower limb in patients with PCL injuries are still not clear.

Methods: Three-dimensional gait analysis system, force plate, electromyography will be used for 55 healthy male participants (control group) and 55 male patients with isolated PCL-deficiency (PCL-d group) during walking, jogging, cutting, jumping. Repeated measurement two-factor analysis of variance will be performed to determine differences between involved and uninvolved legs in the PCL-d group and control group at different rehabilitation times (prior reconstruction surgery, 6 months, and 1-year post PCL reconstruction surgery). Three-dimensional gait analysis and computer-aided analysis technology of plantar pressure information were used to study the changes of PCL after fracture and reconstruction. Based on the plantar pressure information, the movement parameters, and individual attribute parameters, establish a knee joint biomechanical evaluation model to quantify and evaluate the plantar pressure information under dynamic load-bearing state after PCL fracture. Provide a precise basis for the biomechanical state of the knee, and establish a clinically practical automatic analysis of plantar pressure information and an expert diagnostic system.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • age of 18-45 years old
  • Isolated PCL rupture patients: The inclusion criteria included an isolated PCL rupture of at least 3 months' duration.
  • Healthy volunteers: no history of neuro or musculoskeletal system injury that may affect the movements.

排除标准

  • additional knee ligament or meniscal damage
  • severe damage to the ipsilateral hip, ankle joint, or contralateral lower limb (ligament ruptures or bone fractures)
  • age >50 years (to avoid age-induced osteoarthritis interference)
  • any cartilage injury grade >2 according to the Outerbridge classification
  • Tegner score18 <3

结局指标

主要结局

walking speed

时间窗: On the day of enrollment.

Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

ground reaction force

时间窗: On the day of enrollment.

Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

knee flexion angle

时间窗: On the day of enrollment.

Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

the moment of knee extension in the gait cycle

时间窗: On the day of enrollment.

Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

the moment of knee flexion in the gait cycle

时间窗: On the day of enrollment.

Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

次要结局

  • The International Knee Documentation Committee (IKDC) score(On the day of enrollment.)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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