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临床试验/NL-OMON42945
NL-OMON42945已完成不适用

Trained platelets: Long term effects of Gram positive and Gram negative infections on platelet phenotype. - Trained platelets

Radboud Universiteit Nijmegen0 个研究点目标入组 70 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
70

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • •>18 years
  • •Following infections:
  • •o Positive blood culture pathogenic Gram positive bacteria (eg. Staphylococcus aureus (at least 10 with S. aureus), Streptococci)
  • •o Positive blood culture with a pathogenic Gram negative bacteria (eg. E. coli (at least 10 with E. coli), K. pneumoniae)
  • •Expected duration of in-patient care of at least 3 days.
  • •Signed informed consent

排除标准

  • •Use of platelet function inhibitors (except aspirin)
  • •Antibiotic therapy for longer than 72 hours
  • •Myocardial infarction or stroke in the previous year
  • •An active hematologic or solid malignancy
  • •Terminal renal failure requiring dialysis
  • •Insulin dependent diabetes mellitus
  • •Solid organ transplant requiring anti-inflammatory medication
  • •Use of anti-inflammatory agents such as prednison (>7.5mg) or use of targeted biological agents (eg. TNF-blockers, monoclonal antibodies) with the exception of NSAIDs
  • •Micro-organisms that are well known contaminants in a blood culture (e.g. coagulase negative staphylococcus)

研究者

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