NL-OMON52639尚未招募2 期
Matched Unrelated vs. Haploidentical donor for allogeneic stem cell transplantation in patients with Acute Leukemia with identical GVHD prophylaxis - A randomized porspective European trial. - HaploMUD study
niversity Medical Center Hamburg-Eppendorf0 个研究点目标入组 15 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 15
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- AML intermediate or high risk according to ELN or ALL high risk according to
- •ESMO guidelines in 1. CR or AML/ALL in 2. CR, or high risk MDS (according to
- •IPSS-R) in 1. CR or 2. CR.
- •- Patients age 18 - 70 years.
- •- Signed informed consent form
- •- ECOG <= 2
- •- 10/10 HLA-matched unrelated donor and haploidentical (>= 5/10 and <= 8/10 HLA)
- •matched donor
排除标准
- •- Severe renal, hepatic, pulmonary or cardiac disease,
- •- Positive serology for HIV
- •- Pregnant or lactating women
- •- Uncontrolled invasive fungal infection at time of screening (baseline)
- •- Serious psychiatric or psychological disorders
- •- Uncontrolled severe autoimmune disease or uncontrolled other malignancy
- •- Availability of an HLA-identical sibling as donor source
研究者
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