临床试验/NCT06313255

NCT06313255招募中不适用

A Retrospective Observational Study on the Effects of Probiotics on HBsAg Clearance

Qilu Hospital of Shandong University1 个研究点分布在 1 个国家目标入组 40 人开始时间: 2023年5月9日最近更新: 2024年5月1日

适应症

干预措施

试验速览

阶段: 不适用
状态: 招募中
发起方: Qilu Hospital of Shandong University
入组人数: 40
试验地点: 1
主要终点: HBsAg clearance

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The goal of this retrospective observational study is to find out the effects of probiotics on HBV clearance. The main question it aims to answer is:

Are the probiotics have an effect in promoting HBV clearance? The participants will observe the HBV clearance rate in chronic hepatitis B patients receive probiotics in addition to the routine antiviral therapy.

Researchers will compare the HBV clearance rate in chronic hepatitis B patients receive probiotics and antiviral therapy with those receiving solely antiviral therapy.

研究设计

研究类型: Observational
观察模型: Case Only
时间视角: Retrospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•chronic hepatitis B patients

排除标准

•patients with malignancies
•patients with other liver diseases
•pregnancy patients

研究组 & 干预措施

PegIFNα2b

干预措施: PegIFNα2b (Drug)

PegIFNα2b+probiotics

干预措施: PegIFNα2b+probiotics (Drug)

Nucleoside analog

干预措施: Nucleoside analog (Drug)

Nucleoside analog+probiotics

干预措施: Nucleoside analog+probiotics (Drug)

结局指标

主要结局

HBsAg clearance

时间窗: 48 months

次要结局

未报告次要终点

研究者

发起方

Qilu Hospital of Shandong University

申办方类型

Other

责任方

Sponsor

研究点 (1)

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