Effect of Galacto-Oligosaccharides supplementation on amoxicillin-treated gut microbiota from healthy adults : a proof of principal study - GOS-AMX Study

Wageningen Universiteit0 个研究点目标入组 10 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•Age: 18-40
•BMI: 18.5-25 kg/m2
•Stable weight over the last 6 months
•Western diet
•Availability of information about birth by caesarean section and breast-feeding at age 0-3 months
•Regular defecation (~1day)
•Healthy as judge by the participant himself
•Having signed the informed consent form

•Smoking or drug use
•Pregnant (include planning to be or gave birth in the last 6 months) or lactating woman
•Using contraceptive pill
•Gastro-intestinal diseases by the volunteer him/herself or in his/her family (e.g. irritable bowel syndrome, inflammatory bowel disease)
•Traveling to an Asian, African or south American country < 6 months before the study
•Hypersensitivity or food allergy for products used in this study (e.g. Lactose, Penicillin)
•History of pre-existing allergies, such as asthma and hay fever
•Having hepatic disease and renal failure
•Using medication other than paracetamol, acetylsalicylic acid (aspirin), hay fever, asthma
•Not willing to have the family doctor be informed about participation to the study
•Antibiotic use < 3 months before the study
•More than 3 antibiotic treatments in the last 2 years.
•Probiotic or prebiotic use < 1 month before the study*

发起方