Comparison Between Meperidine and Drotaverine Regarding the Effect on the Duration of the First Stage of Labor in Full Term Primigravidae
试验速览
- 阶段
- 2 期
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- the duration of the first stage of labor
研究概览
简要总结
Comparison Between Meperidine and Drotaverine Regarding the Effect on the Duration of the First Stage of Labor in Full Term Primigravidae
详细描述
Comparison Between Meperidine and Drotaverine Regarding the Effect on the Duration of the First Stage of Labor in Full Term Primigravidae
Protocol of Thesis Submitted for partial fulfillment of master degree in Obstetrics & Gynecology
The aim of this work is to compare and to evaluate the efficacy of drotaverine hydrochloride versus meperidine hydrochloride on the duration of the 1st stage of labor.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Double (Participant, Investigator)
入排标准
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •● primigravida.
- •Singleton pregnancy.
- •Term gestation i.e, 38-41 weeks.
- •Sure, reliable dates documented by ultrasound in the 1st half of pregnancy.
- •Vertex presentation with occipito anterior position.
- •Efficient uterine contractions at a rate of at least 3 to 4 contractions every 10 minutes, each contraction lasting for at least 40 seconds.
排除标准
- •● Abnormal presentation or occipito posterior position.
- •Multiple pregnancies.
- •Cephalo-pelvic disproportion.
- •Cervical surgery in the past or history of cervical injury.
- •Patients on antihypertensive therapy.
- •Known hypersensitivity to drotaverine or meperidine.
- •If any other spasmolytic agent had been used within 48 hours.
研究组 & 干预措施
meperidine and duration of 1st stage of labor
meperidine 100mg i.v in 1st stage of labor and calculate the duration of the 1st stage of labor
干预措施: Meperidine (Drug)
drotaverine and duration of 1st stage of labor
drotaverine 40mg i.v in 1st stage of labor and calculate the duration of the 1st stage of labor
干预措施: Drotaverine (Drug)
结局指标
主要结局
the duration of the first stage of labor
时间窗: 6 monthes
the primary outcome is to evaluate whether meperidine or drotaverine is more effective in shortening the duration of the 1st stage of labor
effect on the duration of the 1st stage of labor
时间窗: 6 monthes
the primary outcome is to evaluate whether meperidine or drotaverine is more effective on the duration of the 1st stage of labor
次要结局
- effect on pain(6 monthes)