跳至主要内容
临床试验/NCT03116581
NCT03116581终止不适用

Study on the Parameters That Influence Perceptual Decisions

Hospices Civils de Lyon1 个研究点 分布在 1 个国家目标入组 159 人开始时间: 2014年2月3日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
终止
入组人数
159
试验地点
1
主要终点
Modulation of the decisional parameter by the payoff conditions

研究概览

简要总结

The study aimed to understand how payoffs for others influence perceptual decision making. The research consists in testing how varying monetary payoffs for another modify the perceptual decision making processes. The use of drift diffusion models on a random dots task enable the characterization of the decision parameter(s) that are modulated when a decision is made to win payoffs for others as compared to decisions for self-benefits. Once the parameter revealed through behavioral experiment, neuroimaging is applied to find the neural correlates of the effects of taking others into account in the decision making process.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Aged between 18 and 35
  • •Right-handed
  • •Normal vision or corrected by contact lenses

排除标准

  • •Contraindications to the MEG examination
  • •Presence of a perceptual disorder (vision) or motor impairing the capacity to carry out the tasks requested (including dyschromatopsia and achromatopsia).
  • •Taking of medical treatment in progress (excluding contraceptive pill).
  • •Known neurological or psychiatric history or disorders.
  • •Participants in an exclusion period for any other research.
  • •Participants who do not benefit from social protection.
  • •Participants refusing to be informed of the results of the medical examination.
  • •Participants who refuse to be informed of the possible detection of an anomaly.
  • •Participants with MRI contraindications

研究组 & 干预措施

Vicarious reward

Other

If a decision influences the well-being of another (through monetary payoff), the decision making processes should differ from a decision that would influences only oneself. The difference will be reflected in the reaction-times and in the accuracy of the response to the task. The drift diffusion models care then used to estimate le decision parameter in each condition and understand which parameter is influenced by the beneficiary of the payoff associated with a decision.

Once the decision parameter characterized with behavioral experiment, the study aims to better understand the neural network sustaining the influence of others on the decision making process, by assessing the neural activity related to the decision making processes. Also, the research compares how the brain responses for payoff for others and payoffs for oneself, specially to confirm that these responses are located in different areas of the Anterior cingulate Cortex.

干预措施: Behavior (Other)

Vicarious reward

Other

If a decision influences the well-being of another (through monetary payoff), the decision making processes should differ from a decision that would influences only oneself. The difference will be reflected in the reaction-times and in the accuracy of the response to the task. The drift diffusion models care then used to estimate le decision parameter in each condition and understand which parameter is influenced by the beneficiary of the payoff associated with a decision.

Once the decision parameter characterized with behavioral experiment, the study aims to better understand the neural network sustaining the influence of others on the decision making process, by assessing the neural activity related to the decision making processes. Also, the research compares how the brain responses for payoff for others and payoffs for oneself, specially to confirm that these responses are located in different areas of the Anterior cingulate Cortex.

干预措施: fMRI (functional Magnetic Resonance Imagery) (Other)

Vicarious reward

Other

If a decision influences the well-being of another (through monetary payoff), the decision making processes should differ from a decision that would influences only oneself. The difference will be reflected in the reaction-times and in the accuracy of the response to the task. The drift diffusion models care then used to estimate le decision parameter in each condition and understand which parameter is influenced by the beneficiary of the payoff associated with a decision.

Once the decision parameter characterized with behavioral experiment, the study aims to better understand the neural network sustaining the influence of others on the decision making process, by assessing the neural activity related to the decision making processes. Also, the research compares how the brain responses for payoff for others and payoffs for oneself, specially to confirm that these responses are located in different areas of the Anterior cingulate Cortex.

干预措施: MEG (MagnetoEncephaloGraphy) (Other)

Audience effect

Other

In order to clarify the complex changes in the decision-making processes induced by simple observation by others (audience) , the experiment have two levels of difficulty . These levels of difficulty will be determined in such a way as to achieve better 'public' performance than 'private' when the task is easy (high level of consistency) and poor performance when the task is difficult (low level of coherence) As described in the literature in psychology. Drift diffusion models will be used to better understand the variations in performance, to decipher between a modulation of the diffusion velocity and or of the decision threshold. This study will help characterize how observation by others modulates performance. Once the decision parameter characterized with behavioral experiment, the study aims to better understand the neural network sustaining the impact of observation by others on the decision making process.

干预措施: fMRI (functional Magnetic Resonance Imagery) (Other)

Audience effect

Other

In order to clarify the complex changes in the decision-making processes induced by simple observation by others (audience) , the experiment have two levels of difficulty . These levels of difficulty will be determined in such a way as to achieve better 'public' performance than 'private' when the task is easy (high level of consistency) and poor performance when the task is difficult (low level of coherence) As described in the literature in psychology. Drift diffusion models will be used to better understand the variations in performance, to decipher between a modulation of the diffusion velocity and or of the decision threshold. This study will help characterize how observation by others modulates performance. Once the decision parameter characterized with behavioral experiment, the study aims to better understand the neural network sustaining the impact of observation by others on the decision making process.

干预措施: MEG (MagnetoEncephaloGraphy) (Other)

Audience effect

Other

In order to clarify the complex changes in the decision-making processes induced by simple observation by others (audience) , the experiment have two levels of difficulty . These levels of difficulty will be determined in such a way as to achieve better 'public' performance than 'private' when the task is easy (high level of consistency) and poor performance when the task is difficult (low level of coherence) As described in the literature in psychology. Drift diffusion models will be used to better understand the variations in performance, to decipher between a modulation of the diffusion velocity and or of the decision threshold. This study will help characterize how observation by others modulates performance. Once the decision parameter characterized with behavioral experiment, the study aims to better understand the neural network sustaining the impact of observation by others on the decision making process.

干预措施: Behavior (Other)

结局指标

主要结局

Modulation of the decisional parameter by the payoff conditions

时间窗: 1 hour

behavioral data (reaction-times and accuracy) are collected and the decision parameter can be estimated from them using Drift Diffusion Models

Modulation of the decisional parameter by the beneficiary conditions

时间窗: 1 hour

behavioral data (reaction-times and accuracy) are collected and the decision parameter can be estimated from them using Drift Diffusion Models

次要结局

  • Time-frequency brain responses(1 hour)
  • BOLD(1 hour)
  • Event-Related potentials(1 hour)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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