CTRI/2020/10/028484尚未招募4 期
Impact of passively placed sodium hypochlorite in a calcium hydroxide dressing on root canal disinfection and periapical tissue response: a randomized controlled trial
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- Microbial samples from root canal
研究概览
简要总结
Two types of intracanal medicament will be used (NaOCl + calcium hydroxide and calcium hydroxide alone) and the microbial samples and periapical inflammatory markers will be assessed from the teeth with pulpal necrosis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •pulpal diagnosis of necrosis and an apical diagnosis of symptomatic/asymptomatic apical periodontitis.
排除标准
- •(i) a chronic condition requiring the intake of anti-inflammatory/antibiotic drugs, (ii) tooth which cannot be isolated by rubber dam properly, (iii) a non-restorable tooth, or (iv) root canals in which patency for periapical fluid sampling cannot not be achieved.
结局指标
主要结局
Microbial samples from root canal
时间窗: one week
次要结局
- periapical markers(4 weeks)
研究者
研究点 (1)
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