Intervention Targeting Medication Adherence and Methamphetamine Use in HIV Positive Men
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 210
- 试验地点
- 1
- 主要终点
- Adherence to HIV medication
研究概览
简要总结
The primary aim is to test an innovative 8-session intervention, based on Motivational Interviewing and Cognitive Behavioral Skills-Training for the co-occurrence of methamphetamine use and highly active antiretroviral therapy (HAART) non-adherence among methamphetamine using HIV+ MSM in NYC, compared to an 8-session educational (ED) condition. Participants in the intervention condition will report greater reductions in the number of days of methamphetamine use and viral load, and greater increases in CD4 counts and self-reported and objectively measured adherence than those in the education condition.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •HIV+ (confirmed at baseline through documentation)
- •Biologically male
- •report sex with another man at least once
- •report methamphetamine use at least three times in the past three months
- •report less than 90% HAART medication adherence, as measured by the total number of days a participant missed an HIV medication in the last 30
- •able to communicate with staff and complete a survey that is in English.
排除标准
- •Unstable, serious psychiatric symptoms
- •Currently suicidal/homicidal
- •Evidence of gross cognitive impairment
- •Self-reported current enrollment in a drug or HIV-related intervention or research study.
- •Methadone use
结局指标
主要结局
Adherence to HIV medication
时间窗: every three months over the course of a year
Participants in the intervention condition will report greater reductions in viral load, and greater increases in CD4 counts and self-reported adherence than those in the education comparison at at the end of the intervention period (3 months). Those in the intervention condition will also maintain greater reductions in viral load, and greater increases in CD4 counts and self-reported adherence than those in the education comparison condition at the three follow-up assessments (6, 9, and 12 months).
Methamphetamine use.
时间窗: every three months over the course of a year
Participants in the intervention condition will report greater reductions in self-reported days of methamphetamine use than those in the education comparison at at the end of the intervention period (3 months). Those in the intervention condition will also maintain greater reductions in self-reported days of methamphetamine use than those in the education comparison condition at the three follow-up assessments (6, 9, and 12 months).
次要结局
- Sexual Risk(every three months over the course of a year)
- Polysubstance use(every three months over the course of a year)
研究者
Jeffrey T. Parsons
Professor
Hunter College of City University of New York