Desensitizing ability of different desensitizing agents-An in-vivo study

The aim of the study is to evaluate the desensitizing ability of nano-hydroxyapatite based curodont and gluma -in vivo and to compare the desensitizing efficacy of nano-hydroxyapatite based, curodent and

gluma. patients will be taken from OPD of department of Conservative Dentistry and Endodontics in St. Joseph Dental College, Eluru. Signed informed consent will be taken from all the patients who are diagnosed with dentinal hypersensitivity.

Participants included in the study had the following conditions:

1. Good general health without any known allergy to commercial dental products.

2. The teeth are free of decay or restoration.

3. Patients have not previously received any dentine hypersensitivity treatments.

4. Patients have no history of receiving any teeth whitening treatments.

5. The degree of tooth initial sensitivity should be 3 or higher based on VAS.

Participants excluded from the study had the following conditions:

1. use of medications that could interfere with the perception of pain including chronic

use of anti-inflammatory, analgesic, anticonvulsant, sedative, or other psychotropic drugs

and pregnancy or breastfeeding and patients with chronic diseases.

2. Patients who have been using desensitizing toothpaste or mouthwash in the last 3 months.

3. Patients who had underwent periodontal surgery in the last 6 months.

4. Teeth with evidence of pulpitis, Vital or non-vital teeth that have cracks, previous large restorations, deep abrasions requiring Class V fillings, or had any fractured or endodontically treated teeth carious lesions, gingival recession of more than 3 mm or active periodontal disease.

5. Teeth with deep carious lesions in the vicinity of sensitive teeth that their pain can be confused with tooth sensitivity.

6. Patients whose sensitive teeth are adjacent together.

After recording the initial tooth sensitivity, the patients were randomly divided and intervened with following desensitizing agents i.e, nanohydroxyapatite gel, curodont, and gluma and will be followed up for a period of 3 months. the results will be statistically analyzed.