Effectiveness of Reconditioning Exercise on Mobility and Functional Recovery in Older Adults With Urinary Tract Cancer Following Curative Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Timed up and go test
研究概览
简要总结
As population ages, geriatric patients with urinary tract cancer suffer from more complications and functional decline that alter treatment plan despite advance in cancer surgery. It was found that these urinary tract cancer survivors required a longer time to recover to the state before the treatment, and some may be even unable to recover to the state before the treatment. Exercise intervention has been found to be beneficial to improve functional capacity for cancer survivors, such as breast cancer. However, it is unclear whether exercise intervention could also improve functional recovery and mobility in patients with urinary tract cancer following curative surgery, especially in older adults. The purpose of this study is to investigate the effect of reconditioning exercise on morbidity, oncological outcomes, and functional recovery in older adults with urinary tract cancer following curative surgery.
Patients aged over 65 years old and after having undergone curative surgery for confirmed urinary tract cancer will be recruited. The participants will be assigned into two groups using blocked randomization design. One group will receive reconditioning exercise training for five consecutive days, and the other group will receive exercise education. Structured questionnaire for comprehensive geriatric assessment and functional mobility, such as walking performance, will be used to assess the training effect. Outcome measures are assessed including major complication after surgeries, changes in functional status, tumor progression, and length of survival. Physical function measurement will include hand grip, muscle strength of lower extremities, and gait performance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 100 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •after having undergone curative surgery for confirmed urinary tract cancer
- •able to independently walk for at least 8 meters before surgery
- •able to follow 3-step commands
排除标准
- •having unstable medical conditions or metastasis
- •having neuromuscular diseases, such as stroke, Parkinson's diseases
- •unable to attend training sessions
- •having other health issues which would interfere evaluation and exercise training
结局指标
主要结局
Timed up and go test
时间窗: Follow up at one month after training
Subjects are asked to rise from a standard armchair, walk to a marker 3 m away, turn, walk back, and sit down again.
Six minute walk test
时间窗: Follow up at one month after training
Subjects are instructed to walk as far as possible for 6 minutes.
Muscle strength of the lower extremities
时间窗: Follow up at one month after training
Muscle strength of bilateral hip flexor,knee extensor, ankle dorsiflexor, and ankle plantarflexor
次要结局
- The Short Portable Mental Status Questionnaire (SPMSQ)(Follow up at one month after training)
- Grip strength(Follow up at one month after training)
- Modified Katz Index of Independence in Activities of Daily Living(Follow up at one month after training)
- Lawton instrumental activities of daily living scale(Follow up at one month after training)
- The Short-form Geriatric Depression Scale (GDS)(Follow up at one month after training)
研究者
Pei-Yun Lee
Assistant professor
National Cheng Kung University