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临床试验/CTRI/2025/01/079029
CTRI/2025/01/079029尚未招募不适用

Evaluation Of Comparative Efficacy Of Murivenna Ointment With Povidone Iodine Ointment In Episiotomy Wound.

Matoshree Asrabai Darade Ayurved College Babhulgao Tal-Yeola1 个研究点 分布在 1 个国家目标入组 92 人开始时间: 2025年1月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
92
试验地点
1
主要终点
1)Pain

研究概览

简要总结

Postpartum women face lots of difficulties in sitting, walking, standing, and urination also. So, it is very much necessary that perineum shall be healed as soon as possible to avoid complications. In Sutika paricharya, Episiotomy care is also recommended. This surgical wound can be considered on the lines of Sadyovrana and approached accordingly. Acharya Sushruta has mentioned Shashti Upakramas and Sapta Upakramas for the complete management of Vrana. Taila is one among the sixty treatment modalities from the classics that has been beneficial for controlling pain and healing of the wound. Murivenna - a commonly used Anubutha Yoga listed in Kerala Ayurveda pharmacopeia has Vedhanasthapaka and Shothagna effect. The same reference of Murivenna is quoted in Ayurveda Formulary of India (AFI) Part 3[7]. It promotes fast recovery from both fresh and chronic wounds and ulcers. Application of  Ointment is quite easy than oil and it can be applied in any time even during working hours. It is also being a cost-effective therapy. Hence in the present study, the efficacy of Murivenna ointment application on episiotomy wound will be observed under aseptic precaution.

Ayurveda is not only rich in medicine but also in the field of surgery. Acharya Sushruta is the founder of classical Indian surgery, he has discussed the fundamental concepts underlying injuries, wound healing, etc. The delivery process might be simplified by Yoniprasarana (Dilating vulval orifice for easy delivery) by surgical intervention i.e. episiotomy to prevent the aforementioned injuries.  The cut is known as a vitapcheda because it occurs on vitap Pradesh. Episiotomy prevents blood loss, postpartum pelvic floor dysfunction, and perineal and neonatal trauma. Episiotomy is defined as a deliberate incision taken on the perineum and the posterior vaginal wall during the second stage of labour to prevent greater maternal and fetal injurie. Episiotomy is a surgical procedure that is frequently utilized today to facilitate easy delivery of a newborn. In order to increase the vaginal introitus during the second stage of labor, an episiotomy is performed.A straight incision is simpler to repair and heals better than a jagged,uncontrolled laceration.

Restoring the Ayurvedic surgical terms that were described hundreds of years ago might give one’s own abilities and resources when doing surgical procedures. The most frequent presentation during a routine vaginal delivery is the vertex presentation. The birth canal of female body hardly allows engaging the diameter of head in vertex presentation during the process of normal delivery. Because of this, the perineum cannot withstand such a strong force without tearing and lacerating the vaginal wall. According to Ayurveda, Marma & Marma like organ surrounds the Tryavarta Yoni region. Since Vitap marma is located in the inguinal region and damage to it may result in Shandhata, the perineum region is also known as Vitap Pradesh. Injuries to the urethra, anal area, and rectum can happen during vaginal birth. Damage to these organs may result in Vaikalyata. There are many degrees of maternal passageway rips that can result in immediate consequences including hemorrhage, haematoma, infections, tears, and distant complications like urinary incontinence and organ prolapse. Samhitas state that Basti and Guda are Sadhyapranhara Marma.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 35.00 Year(s)(—)
性别
Female

入选标准

  • Patient of age group between 18 to 35 years will be selected.
  • Patients who have undergone mediolateral episiotomy sutured wound will be selected .
  • Both Primi and Multi para will be selected.

排除标准

  • All degree perineal tear cases will be excluded.
  • Patients having blood coagulopathy, hematoma and abscess will be excluded.
  • HIV, HbsAg and VDRL cases will be excluded.
  • Patient having Diabetes mellitus will be excluded .
  • Previous episiotomy resutured wound,Keloid formed wound, will be excluded.

结局指标

主要结局

1)Pain

时间窗: Day 0,Day 1,Day 2,Day3,Day 7,Day 10

2)Pricking sensation

时间窗: Day 0,Day 1,Day 2,Day3,Day 7,Day 10

3)Redness at wound

时间窗: Day 0,Day 1,Day 2,Day3,Day 7,Day 10

4)Oedema at wound

时间窗: Day 0,Day 1,Day 2,Day3,Day 7,Day 10

4)Ecchymosis

时间窗: Day 0,Day 1,Day 2,Day3,Day 7,Day 10

5)Discharge from Wound

时间窗: Day 0,Day 1,Day 2,Day3,Day 7,Day 10

6)Approximation of Wound

时间窗: Day 0,Day 1,Day 2,Day3,Day 7,Day 10

7)Tenderness

时间窗: Day 0,Day 1,Day 2,Day3,Day 7,Day 10

次要结局

  • Above all the symptoms will be decreased(Maximum 10 days)

研究者

发起方
Matoshree Asrabai Darade Ayurved College Babhulgao Tal-Yeola
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Snehal Bapu Borse

Matoshri Asrabai Darade Ayurved College,Babhulgao,Yeola

研究点 (1)

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