Retrospective and Prospective Evaluation of the Impact of Innovative and Conventional Treatments and of Clinical Variables on the Outcome of Thyroid Cancer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 3,000
- 试验地点
- 1
- 主要终点
- Dynamic risk stratification
研究概览
简要总结
DTC has a generally favorable prognosis. The possibility to discriminate between patients with aggressive tumors and those with a more indolent behavior may reduce the need for unnecessary treatments. Aim of this observational study is to evaluate how anamnestic, clinical, and histopathological variables may influence the outcome of the enrolled patients, both regarding morbidity and mortality and in terms of therapeutic choices. The study aims to evaluate the prognostic impact of the therapeutic interventions in terms of efficacy and regarding the appearance of adverse events.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •thyroid cancer diagnosis
排除标准
- •patients unable to sign informed consent
结局指标
主要结局
Dynamic risk stratification
时间窗: ten years from the primary treatment
impact of the different variables on the DRS
Overall survival
时间窗: ten years from the primary treatment
impact of the different variables on the OS in patients treated with TKI for advanced thyroid cancer
Progression-free survival
时间窗: ten years from the primary treatment
impact of the different variables on the PFS in patients treated with TKI for advanced thyroid cancer
次要结局
未报告次要终点
