跳至主要内容
临床试验/NCT05752604
NCT05752604招募中不适用

Retrospective and Prospective Evaluation of the Impact of Innovative and Conventional Treatments and of Clinical Variables on the Outcome of Thyroid Cancer

Istituto Auxologico Italiano1 个研究点 分布在 1 个国家目标入组 3,000 人开始时间: 2022年7月12日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
3,000
试验地点
1
主要终点
Dynamic risk stratification

研究概览

简要总结

DTC has a generally favorable prognosis. The possibility to discriminate between patients with aggressive tumors and those with a more indolent behavior may reduce the need for unnecessary treatments. Aim of this observational study is to evaluate how anamnestic, clinical, and histopathological variables may influence the outcome of the enrolled patients, both regarding morbidity and mortality and in terms of therapeutic choices. The study aims to evaluate the prognostic impact of the therapeutic interventions in terms of efficacy and regarding the appearance of adverse events.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • thyroid cancer diagnosis

排除标准

  • patients unable to sign informed consent

结局指标

主要结局

Dynamic risk stratification

时间窗: ten years from the primary treatment

impact of the different variables on the DRS

Overall survival

时间窗: ten years from the primary treatment

impact of the different variables on the OS in patients treated with TKI for advanced thyroid cancer

Progression-free survival

时间窗: ten years from the primary treatment

impact of the different variables on the PFS in patients treated with TKI for advanced thyroid cancer

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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