Comparative evaluation of efficacy of Acacia catechu willd and Chlorhexidine as mouthwash on Gingivitis- A clinicomicrobiological study
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- reduction of clinical signs
研究概览
简要总结
Acacia catechu Willd (Khadir) belonging to Family-Fabaceae and subfamily-Mimosoideae is a historical plant which has a valuable importance because of its medicinal properties. Acacia catechu exhibits various pharmacological effects like anti-inflammatory, anti-diarrhoeal, hypoglycemic, antioxidant, hepatoprotective, antipyretic, antimicrobial, anticancer, antibacterial, anti-ulcer and antisecretory activities, sore throat and wound healing etc.Acacia catechu is also useful as a topical agent for sore gums and mouth ulcers. Thus the plant has diverse pharmacological actions.
Acacia catechu extract may act as a good oral hygiene product because of its antimicrobial and anti-inflammatory activity. Since, there are no studies regarding the efficacy of Acacia catechu as a mouthwash, this study is carried out to assess the efficacy of Acacia catechu as mouthwash in treatment of gingivitis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Willingness to comply with the study protocol.
- •2.Subjects who are diagnosed with Chronic generalized gingivitis.
- •3.Systemically healthy individuals.
- •4.Minimum of 10 gradable teeth.
排除标准
- •1.Subjects suffering from any known systemic diseases.
- •2.Unable or not willing to comply with the study protocol.
- •3.Lactating and pregnant females.
- •4.Subjects who are smokers.
- •5.Subjects who have received any periodontal therapy in the last 6 months.
结局指标
主要结局
reduction of clinical signs
时间窗: 0 and 15th day
次要结局
- comparing effects of Acacia catechu mouthwash and Chlorhexidine on Gingivitis(0 and 15th day)