Effects of an 8-month Yoga Intervention on Bone Metabolism in Healthy Middle-aged Premenopausal Women: A Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 47
- 试验地点
- 2
- 主要终点
- Change in bone mineral density from baseline to 8 months
研究概览
简要总结
This study examined the effects of 8 months of Yoga training on bone density and bone turnover markers in premenopausal women, ages 35-50 years. The style of Yoga used was power Yoga that involved postures with a jumping component. The investigators hypothesized that the Yoga intervention would result in beneficial improvements in bone turnover markers, by increasing the bone formation marker and decreasing the bone resorption marker.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 35 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •participants had not been engaged in resistance training or in Yoga exercise for at least 12 months prior to the study
- •did not have chronic back or joint problems or cardiovascular disease
- •not taking antihypertensive drugs or any medication that affects bone density
- •not taking hormonal contraception
- •they self-reported having regular menstrual cycles.
排除标准
- •body weight more than 300 pounds
结局指标
主要结局
Change in bone mineral density from baseline to 8 months
时间窗: pre and post 8 months training
change in bone turnover markers
时间窗: pre and post 8 month intervention
change in tibia bone characteristics
时间窗: pre and post 8 month intervention
changes in volumetric bone mineral density and bone strength of the non-dominant tibia assessed by peripheral Quantitative Computed Tomography (pQCT)
Changes in muscular strength
时间窗: pre and post 9 month intervention
Isotonic 1 repetition maximum (1RM) for 4 lower body and 2 upper body resistance exercises
Change in arterial compliance
时间窗: pre and post 8 month interventon
Arterial compliance of the large and small arteries was assessed using Pulse Contour analysis.
Change in Insulin-like Growth Factor-1 (IGF-I) and Insulin-like Growth Factor BP3 (IGFBP3)
时间窗: pre and post 8 month intervention
次要结局
- Daily Calcium intake(pre and post 8 month intervention)
- Menstrual History(pre and post 8 month intervention)
- Dietary intake(At baseline at the same time as other outcomes, about 2 weeks before the beginning of the yoga training)
- Change in physical activity levels(pre and post 8 month intervention)
- Change in body composition(pre and post 8 month intervention)
研究者
Debra Bemben
Professor
University of Oklahoma