Pilot Study of Performance-based Reinforcement to Enhance Cognitive Remediation Therapy for Substance Users
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Improvement in performance scores on computerized cognitive remediation tasks
研究概览
简要总结
The purpose of this study is to investigate whether monetary reinforcement for performance will enhance the effects of cognitive remediation therapy for substance users seeking treatment at an outpatient facility.
详细描述
Forty individuals seeking treatment for an alcohol or cocaine use disorder at the Substance Abuse Treatment Unit (SATU) will be randomized to receive cognitive remediation therapy with or without additional compensation based on performance. Participants will use the computerized cognitive remediation program (PSSCogRehab 2012) three times per week for four weeks. The primary outcome measure will be an improved performance on the computerized tasks, with secondary outcomes of changes in cognitive functioning (e.g., attention, concentration, memory) as measured by neuropsychological tests between baseline and post-treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 to 60 years old
- •Primary Alcohol and/or Cocaine Abuse/Dependence Diagnosis
- •Abstinence from all drugs/alcohol for 30 days
- •Mild cognitive impairment
- •Sufficiently stable and plan to commit to 4 weeks of outpatient treatment
- •Fluent in English and 6th grade reading ability
排除标准
- •Severe cognitive impairment indicative of dementia
- •Untreated bipolar or psychotic disorder
- •Have current legal case pending such that incarceration during 4-week study is likely
结局指标
主要结局
Improvement in performance scores on computerized cognitive remediation tasks
时间窗: 4 weeks
Performance scores on various computerized cognitive remediation tasks will be measured repeatedly during the 4 week study. These scores include "time to completion", "number of errors", "number of words correctly recalled", and "percentage of task completed"
次要结局
- Improved cognitive function on neuropsychological tests(4 weeks)