Double blind randomized clinical trial comparing noradrenaline plus placebo versus noradrenaline plus terlipressin in septic shock

Fundación Pública Andaluza para la Gestión de la0 个研究点目标入组 152 人开始时间: 2021年7月27日最近更新: 2021年11月8日

试验速览

暂无简介。

•1. Adult patients (18 years or older).
•2. Patients with septic shock.
•3. Patients with a SOFA index> 4 points.
•4. Venous oxygen saturation (SvO2)> 70%
•5. Central venous pressure (CVP)> 8 mmHg.
•6. Signature of the informed consent by the patient or his or her legal representative.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 114
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 38

•1. Pregnant or lactating patients.
•2. Pathologies on which terlipressin is clinically indicated: gastrointestinal bleeding due to esophageal-gastric varices, hepatorenal syndrome.
•3. Patients diagnosed with unstable acute coronary syndrome.
•4. Patients with acute or chronic mesenteric ischemia.
•5. Patients with Raynaud's Phenomenon, or vasospastic disease.
•6. Patients participating in another intervention clinical trial.
•7. Patients with active bleeding.
•8. Patients with renal replacement technique at the time of randomization.
•9. Patients with some limitation of life support treatment (LLST).
•10. Previous use of terlipressin during your stay in the ICU.

发起方

Fundación Pública Andaluza para la Gestión de la