Preservation of Fat Free Mass During Weight Loss
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 29
- 主要终点
- Fat Free Mass
研究概览
简要总结
In this study, we aimed to examine the effect of whey protein supplementation given before night sleep on Fat Free Mass (FFM) preservation during a 4 wk period on Very Low Caloric Diet (VLCD).
Half of the participants underwent a 4 week VLCD and walking program, while the other half underwent a 4 week VLCD, walking program and had an additional protein supplement before each night sleep.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
盲法说明
Single blinded
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Body Mass Index (kg/m^2) > 28
- •Age between 18 and 55 years
排除标准
- •Participation in regular resistance-, aerobic- or anaerobic training (>1 h/wk within the last 3 month before intervention start)
- •Diabetes Physical disabilities that would hinder completion of the walking program.
研究组 & 干预措施
Protein group
4 weeks of a Very Low Calorie Diet (VLCD) + walking program. Whey protein supplementation 0.4g/kg before sleep.
干预措施: Whey protein supplementation (Dietary Supplement)
Protein group
4 weeks of a Very Low Calorie Diet (VLCD) + walking program. Whey protein supplementation 0.4g/kg before sleep.
干预措施: walking program (Other)
Protein group
4 weeks of a Very Low Calorie Diet (VLCD) + walking program. Whey protein supplementation 0.4g/kg before sleep.
干预措施: Very Low Calorie Diet (Other)
Placebo group
4 weeks of a Very Low Calorie Diet (VLCD) + walking program
干预措施: walking program (Other)
Placebo group
4 weeks of a Very Low Calorie Diet (VLCD) + walking program
干预措施: Very Low Calorie Diet (Other)
结局指标
主要结局
Fat Free Mass
时间窗: Change from baseline to after the 4 week intervention period
Dual energy X-ray absorptiometry (DXA)
次要结局
- Oral glucose tolerance test(Change from baseline to after the 4 week intervention period)
- Nitrogen balance(Change in nitrogen content from baseline to day 7 and 28 of the intervention period)
- Fitness level(Change from baseline to after the 4 week intervention period)
- Blood pressure(Change from baseline to after the 4 week intervention period)
- Fat mass(Change from baseline to after the 4 week intervention period)
- waist circumference(Change from baseline to after the 4 week intervention period)
- Performance test(Change from baseline to after the 4 week intervention period)