Use of Oxygen Nebulizer for Preventing Post-operative Sore Throat
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,036
- 试验地点
- 2
- 主要终点
- The effect of oxygen nebulizer therapy on post-operative sore throat
研究概览
简要总结
Rationale: Delivery dry gas during anesthesia is associated with post-operative sore throat (POST). Oxygen nebulizer therapy increases humidity to the airway, especially post-extubation.
Objective: To investigate the effect and complications of oxygen nebulizer therapy on POST.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-75 years
- •Pre-operative Hb >10 g% or Hct > 30%
- •American Society of Anesthesiologist (ASA) class I-III
- •Elective surgery
- •General anesthesia with oroendotracheal tube using Macintosh laryngoscope
- •Not exposed to intraoperative nitrous oxide
- •Oxygen saturation at room air > 95% before induction and at arrival the PACU
排除标准
- •Cases needing ICU admission immediately post-operative
- •Conditioning requiring post-operative oxygen therapy e.g. heart disease, pregnancy, morbid obesity, cardiac and thoracic surgery
- •Patients' conditioning affecting to complication of nebulizer oxygen therapy e.g. pulmonary disease, bleomycin treatment
- •Patient's conditioning affecting POST assessment e.g. pre-operative using ventilator, recent upper respiratory tract infection (URI), recent lower respiratory tract infection and history of difficult airway
- •Surgical conditioning affecting POST e.g. airway surgery, oral surgery, esophageal and neck surgery
结局指标
主要结局
The effect of oxygen nebulizer therapy on post-operative sore throat
时间窗: at post-anesthetic care unit and 24-h post-operative
Assess POST using scoring system and discomfort by interview. Sore throat scoring system is divided into 4 scores 0 means no sore throat 1. means minimal sore throat (less severe than cold) 2. means moderate sore throat (similar to cold) 3. means severe sore throat (more severe than cold)
次要结局
- To evaluate the adverse events (pulmonary complications, wound infection, and mortality) of post-operative complications related to oxygen therapy(24-h post-op and 30-d mortality)
研究者
Panthila Rujirojindakul
Assistant Professor Dr.Panthila Rujirojindakul
Prince of Songkla University