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临床试验/NCT05997940
NCT05997940招募中不适用

Evaluation Of The Postoperative Analgesic Effectiveness Of The Pericapsular Nerve Group Block Performed Before Spinal Anesthesia In Hip Surgery

Aydin Adnan Menderes University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2022年10月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
50
试验地点
1
主要终点
Numeric Rating Scale (NRS) for postoperative analgesic efficacy

研究概览

简要总结

The target population of hip surgery is usually the elderly patients with systemic comorbidity. Especially hip fractures are common in society and cause high morbidity and mortality for geriatric patients . Pain felt before and during surgery can cause metabolic and endocrine changes in the body, leading to sleep disorders, depression, delirium, dementia and persistent chronic pain. With effective postoperative analgesia, it is possible to reduce postoperative complications and mortality and accelerate post-surgical recovery. Pharmacological methods such as opioids and NSAIDs used for this may cause further deterioration and other side effects in geriatric patients with reduced renal and hepatic function, thus delaying post-surgical recovery and thus discharge. In order to avoid these side effects, regional anesthesia techniques can be preferred.

Regional anesthesia techniques are among the most effective methods of postoperative analgesia. Peripheral nerve blocks are also one of the regional anesthesia methods. Peripheral nerve blocks; They are the most ideal postoperative analgesia methods because they provide effective analgesia, reduce the need for opioids and consequently their side effects, are effective in the treatment of dynamic pain and facilitate recovery.

Patients undergoing hip surgery have very severe pain and need additional postoperative analgesics. Mobilization of patients is delayed due to pain . Depending on this , thromboembolism , deep vein The risk of nosocomial infection increases due to thrombosis , wound infection and increased length of stay.

Alleviating the pain around the hip joint capsule is an effective analgesia method in hip surgeries. The anterior capsule of the hip joint is innervated by the femoral , obturator , and accessory obturator nerves . Pericapsular nerve group (PENG) block also targets these nerves. Many studies have shown that PENG block provides adequate analgesia for more than 24 hours postoperatively. PENG block is a method that is frequently used in the world and in our clinic and has a low complication rate.

In this study, the investigators aimed to show that pericapsular nerve group block performed before spinal anesthesia in hip surgeries reduces postoperative pain and decreases total opioid consumption.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with written informed consent
  • Patients over 18 years old
  • Patients with ASA score I-II-III
  • Patients performed spinal anesthesia for surgery

排除标准

  • Patients without written informed consent
  • Patients with ASA score IV and above
  • Patients who cannot be communicated
  • Patients with infection at the block site
  • Patients with coagulation disorders
  • Patients not suitable for spinal anesthesia
  • Patients with liver and kidney failure
  • Patients who are allergic to the drugs used
  • Patients with major complications during the operation

研究组 & 干预措施

PENG

Active Comparator

PENG block performed before spinal anesthesia

干预措施: PENG block (Drug)

结局指标

主要结局

Numeric Rating Scale (NRS) for postoperative analgesic efficacy

时间窗: Postoperative 24. hour

NRS is a one-dimensional scale used to measure pain intensity. The patient is asked to select the number that best describes the level of pain as 0 = no pain and 10 = worst pain (unbearable).

次要结局

  • Amounts of postoperative analgesic consumption(Postoperative 24 hours)

研究者

发起方
Aydin Adnan Menderes University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Mustafa Ogurlu

Professor Doctor

Aydin Adnan Menderes University

研究点 (1)

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