A Prospective Study Comparing the Mifne Approach of Treating Childhood Autism With Routine Standard Treatment
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- ADOS scores at 3 and 6 months after commencement of treatment
研究概览
简要总结
The current study aims at comparing outcomes achieved using the Mifne approach of treating autistic children with results obtained when routine standard treatment is used. A prospective comparative study will be performed comparing the results of 12 children treated at Mifne with 12 children treated with treatment as usual. A child and adolescent psychiatrist using the Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Schedule-Generic (ADOS-G) will make the diagnostic assessment and a developmental psychologist will make the developmental and psychological assessments using the Vineland Adaptive Behavior Scales-Revised and the Bayley Scales of Infant Development (BSID II) before the child enters the study. Each child will be reassessed following completion of the Mifne intervention, at three and at six months after commencement of treatment. The control child will also be reassessed at three and at six months after commencement of a therapeutic intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 2 Years 至 5 Years(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All children between the ages of 2-5 years who meet diagnostic criteria for Autism or Pervasive Developmental Disorder by DSM IV criteria who are referred for treatment at Mifne for the treatment group.
- •The control group will consist of children meeting the same criteria who are referred to Schneider Children's Medical Center of Israel (SCMCI). Matching will be for age, sex, ethnicity, socioeconomic status, IQ, language development and diagnosis.
- •Exclusion criteria:
- •All referred children who do not meet criteria for Autism or PDD or do not understand Hebrew.
排除标准
- 未提供
结局指标
主要结局
ADOS scores at 3 and 6 months after commencement of treatment
时间窗: 2.5 years
次要结局
- CGI-I score after 3 and 6 months(2.5 years)
研究者
alan apter
Director, Feinberg Child Study Center and Department of Psychiatry, Schneider's Children's Medical Center of Israel
Rabin Medical Center
